Niamh Moran
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Explore the profile of Niamh Moran including associated specialties, affiliations and a list of published articles.
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46
Citations
783
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Recent Articles
1.
Breen C, OConnell J, Geoghegan J, OShea D, Birney S, Tully L, et al.
Obes Facts
. 2022 Oct;
15(6):736-752.
PMID: 36279848
Background: This Clinical Practice Guideline (CPG) for the management of obesity in adults in Ireland, adapted from the Canadian CPG, defines obesity as a complex chronic disease characterised by excess...
2.
Comer S, Le Chevillier A, Szklanna P, Kelliher S, Saeed K, Cullen S, et al.
Front Cardiovasc Med
. 2022 Feb;
9:824601.
PMID: 35224056
Background: Vaccine-induced thrombotic thrombocytopenia (VITT) post SARS-CoV-2 vaccination is characterized by thrombocytopenia and severe thrombosis. Platelet function during patient recovery in the medium-/long-term has not been investigated fully. Here, we...
3.
Comer S, Cullivan S, Szklanna P, Weiss L, Cullen S, Kelliher S, et al.
PLoS Biol
. 2021 Feb;
19(2):e3001109.
PMID: 33596198
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date. Although high rates of venous thromboembolism and...
4.
Stanton A, James K, Brennan M, ODonovan F, Buskandar F, Shortall K, et al.
Sci Rep
. 2020 Sep;
10(1):15444.
PMID: 32963294
Diets low in seafood omega-3 polyunsaturated fatty acids (PUFAs) are very prevalent. Such diets have recently been ranked as the sixth most important dietary risk factor-1.5 million deaths and 33...
5.
Adamson K, Spain E, Prendergast U, Forster R, Moran N, Keyes T
Biomater Sci
. 2020 Jun;
2(10):1509-1520.
PMID: 32481925
Blood platelet adhesion is crucial in dictating haemocompatibility of medical implants and in platelet capture in diagnostics. Understanding the role of platelet activation in dictating platelet adhesion at chemically modified...
6.
Murphy S, Lim S, Kinsella J, Tierney S, Egan B, Feeley T, et al.
Thromb Haemost
. 2019 Feb;
119(5):821-833.
PMID: 30769362
Introduction: Cerebral micro-embolic signals (MES) predict risk of stroke in carotid stenosis patients. However, MES-negative 'recently symptomatic patients' also have a higher stroke risk than 'asymptomatic patients'. Differences in platelet...
7.
OBrien K, Golla K, Kranjc T, ODonovan D, Allen S, Maguire P, et al.
PLoS One
. 2019 Jan;
14(1):e0210337.
PMID: 30689642
Therapeutic modulation of protein interactions is challenging, but short linear motifs (SLiMs) represent potential targets. Focal adhesions play a central role in adhesion by linking cells to the extracellular matrix....
8.
Golla K, Stavropoulos I, Shields D, Moran N
R Soc Open Sci
. 2018 Nov;
5(10):172347.
PMID: 30473799
The juxtamembrane domains (JMD) of transmembrane proteins are rich in critical peptide sequences that participate in dynamic cell signalling events. Synthetic JMD peptides derived from cadherin cell adhesion proteins have...
9.
Adamson K, Spain E, Prendergast U, Moran N, Forster R, Keyes T
Langmuir
. 2017 Dec;
34(2):715-725.
PMID: 29240434
Human blood platelets and SK-N-AS neuroblastoma cancer-cell capture at spontaneously adsorbed monolayers of fibrinogen-binding motifs, GRGDS (generic integrin adhesion), HHLGGAKQAGDV (exclusive to platelet integrin αβ), or octanethiol (adhesion inhibitor) at...
10.
Elaskalani O, Falasca M, Moran N, Berndt M, Metharom P
Cancers (Basel)
. 2017 Oct;
9(10).
PMID: 29064388
Platelets have been demonstrated to be vital in cancer epithelial-mesenchymal transition (EMT), an important step in metastasis. Markers of EMT are associated with chemotherapy resistance. However, the association between the...