Niamh H Foley
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Explore the profile of Niamh H Foley including associated specialties, affiliations and a list of published articles.
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10
Citations
534
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Recent Articles
1.
Curtis A, Fagundes C, Yang G, Palsson-McDermott E, Wochal P, Mcgettrick A, et al.
Proc Natl Acad Sci U S A
. 2015 May;
112(23):7231-6.
PMID: 25995365
The response to an innate immune challenge is conditioned by the time of day, but the molecular basis for this remains unclear. In myeloid cells, there is a temporal regulation...
2.
Watters K, Bryan K, Foley N, Meehan M, Stallings R
BMC Cancer
. 2013 Apr;
13:184.
PMID: 23565812
Background: Ultra-conserved regions (UCRs) are segments of the genome (≥ 200 bp) that exhibit 100% DNA sequence conservation between human, mouse and rat. Transcribed UCRs (T-UCRs) have been shown to...
3.
Foley N, ONeill L
J Leukoc Biol
. 2012 May;
92(3):521-7.
PMID: 22645244
miRNAs are small noncoding RNAs that act as regulators of gene expression. Dysregulation of miRNAs has been shown to contribute to multiple disease processes. It has become apparent that miRNAs...
4.
Stallings R, Foley N, Bray I, Das S, Buckley P
Semin Cancer Biol
. 2011 Jul;
21(4):283-90.
PMID: 21771658
Many neuroblastoma cell lines can be induced to differentiate into a mature neuronal cell type with retinoic acid and other compounds, providing an important model system for elucidating signalling pathways...
5.
Bray I, Tivnan A, Bryan K, Foley N, Watters K, Tracey L, et al.
Cancer Lett
. 2011 Feb;
303(1):56-64.
PMID: 21310526
Several studies have implicated the dysregulation of microRNAs in neuroblastoma pathogenesis, an often fatal paediatric cancer arising from precursor cells of the sympathetic nervous system. Our group and others have...
6.
Tivnan A, Foley N, Tracey L, Davidoff A, Stallings R
Anticancer Res
. 2010 Dec;
30(11):4391-5.
PMID: 21115884
Background: Neuroblastoma is a paediatric cancer which originates from precursor cells of the sympathetic nervous system. Previous studies have shown that miR-184 expression has anti-proliferative effects in neuroblastoma cells grown...
7.
Stallings R, Foley N, Bryan K, Buckley P, Bray I
Expert Opin Ther Targets
. 2010 Jul;
14(9):951-62.
PMID: 20658962
Importance Of The Field: Neuroblastomas arise from precursor cells of the sympathetic nervous system and are noted for highly heterogeneous clinical behavior. These tumors currently account for approximately 15% of...
8.
MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2
Foley N, Bray I, Tivnan A, Bryan K, Murphy D, Buckley P, et al.
Mol Cancer
. 2010 Apr;
9:83.
PMID: 20409325
Background: Neuroblastoma is a paediatric cancer of the sympathetic nervous system. The single most important genetic indicator of poor clinical outcome is amplification of the MYCN transcription factor. One of...
9.
Murphy D, Buckley P, Bryan K, Das S, Alcock L, Foley N, et al.
PLoS One
. 2009 Dec;
4(12):e8154.
PMID: 19997598
Background: Neuroblastoma, a cancer derived from precursor cells of the sympathetic nervous system, is a major cause of childhood cancer related deaths. The single most important prognostic indicator of poor...
10.
Bray I, Bryan K, Prenter S, Buckley P, Foley N, Murphy D, et al.
PLoS One
. 2009 Nov;
4(11):e7850.
PMID: 19924232
MiRNAs regulate gene expression at a post-transcriptional level and their dysregulation can play major roles in the pathogenesis of many different forms of cancer, including neuroblastoma, an often fatal paediatric...