Niall Dillon
Overview
Explore the profile of Niall Dillon including associated specialties, affiliations and a list of published articles.
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35
Citations
2152
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Recent Articles
1.
Roman-Trufero M, Dillon N
Front Cell Dev Biol
. 2022 Dec;
10:1058751.
PMID: 36578786
Ubiquitination of cellular proteins plays critical roles in key signalling pathways and in the regulation of protein turnover in eukaryotic cells. E2 ubiquitin conjugating enzymes function as essential intermediates in...
2.
Thomsen I, Kunowska N, de Souza R, Moody A, Crawford G, Wang Y, et al.
J Immunol
. 2021 Nov;
207(12):2976-2991.
PMID: 34810221
RUNX1 is a transcription factor that plays key roles in hematopoietic development and in hematopoiesis and lymphopoiesis. In this article, we report that RUNX1 regulates a gene expression program in...
3.
Sarkar M, Martufi M, Roman-Trufero M, Wang Y, Whilding C, Dormann D, et al.
Mol Biol Cell
. 2021 Oct;
32(22):ar40.
PMID: 34613789
Mesendoderm cells are key intermediate progenitors that form at the early primitive streak (PrS) and give rise to mesoderm and endoderm in the gastrulating embryo. We have identified an interaction...
4.
Roman-Trufero M, Ito C, Pedebos C, Magdalou I, Wang Y, Karimi M, et al.
Mol Biol Evol
. 2020 Mar;
37(7):1986-2001.
PMID: 32145025
Genetic variation in the enzymes that catalyze posttranslational modification of proteins is a potentially important source of phenotypic variation during evolution. Ubiquitination is one such modification that affects turnover of...
5.
Cordonnier G, Mandoli A, Cagnard N, Hypolite G, Lhermitte L, Verhoeyen E, et al.
Cell Rep
. 2020 Jan;
30(2):299-307.e3.
PMID: 31940477
Mutations and deletions of polycomb repressive complex (PRC) components are increasingly recognized to affect tumor biology in a range of cancers. However, little is known about how genetic alterations of...
6.
Beagrie R, Scialdone A, Schueler M, Kraemer D, Chotalia M, Xie S, et al.
Nature
. 2017 Mar;
543(7646):519-524.
PMID: 28273065
The organization of the genome in the nucleus and the interactions of genes with their regulatory elements are key features of transcriptional control and their disruption can cause disease. Here...
7.
Bond J, Domaschenz R, Roman-Trufero M, Sabbattini P, Ferreiros-Vidal I, Gerrard G, et al.
Oncotarget
. 2016 Sep;
7(40):65923-65936.
PMID: 27588474
Ikaros and Foxp1 are transcription factors that play key roles in normal lymphopoiesis and lymphoid malignancies. We describe a novel physical and functional interaction between the proteins, which requires the...
8.
Pombo A, Dillon N
Nat Rev Mol Cell Biol
. 2015 Mar;
16(4):245-57.
PMID: 25757416
The different cell types of an organism share the same DNA, but during cell differentiation their genomes undergo diverse structural and organizational changes that affect gene expression and other cellular...
9.
Kunowska N, Rotival M, Yu L, Choudhary J, Dillon N
Nucleic Acids Res
. 2015 Jan;
43(3):1418-32.
PMID: 25605797
The large number of chemical modifications that are found on the histone proteins of eukaryotic cells form multiple complex combinations, which can act as recognition signals for reader proteins. We...
10.
Sabbattini P, Sjoberg M, Nikic S, Frangini A, Holmqvist P, Kunowska N, et al.
Mol Biol Cell
. 2014 Jan;
25(6):904-15.
PMID: 24430871
Methylated histones H3K9 and H3K27 are canonical epigenetic silencing modifications in metazoan organisms, but the relationship between the two modifications has not been well characterized. H3K9me3 coexists with H3K27me3 in...