Nguyen Ky Phat
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Explore the profile of Nguyen Ky Phat including associated specialties, affiliations and a list of published articles.
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13
Citations
37
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Recent Articles
1.
Nhung T, Phat N, Anh T, Nghi T, Thu N, Lee A, et al.
Chem Biol Interact
. 2025 Feb;
411:111448.
PMID: 40015660
A comprehensive understanding of isoniazid (INH)-mediated hepatotoxic effects is essential for developing strategies to predict and prevent severe liver toxicity in tuberculosis treatment. In this study, we used multi-omics profiling...
2.
Anh N, Lee A, Phat N, Yen N, Thu N, Tien N, et al.
PLoS One
. 2024 Oct;
19(10):e0311810.
PMID: 39432469
There is an urgent need for better biomarkers for the detection of early-stage breast cancer. Utilizing untargeted metabolomics and lipidomics in conjunction with advanced data mining approaches for metabolism-centric biomarker...
3.
Anh N, Phat N, Thu N, Tien N, Eunsu C, Kim H, et al.
Sci Rep
. 2024 Jul;
14(1):15312.
PMID: 38961191
Nontuberculous mycobacteria (NTM) infection diagnosis remains a challenge due to its overlapping clinical symptoms with tuberculosis (TB), leading to inappropriate treatment. Herein, we employed noninvasive metabolic phenotyping coupled with comprehensive...
4.
Anh N, Yen N, Tien N, Phat N, Park Y, Kim H, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Feb;
1870(4):167064.
PMID: 38342417
Tracking alterations in polar metabolite and lipid levels during anti-tuberculosis (TB) interventions is an emerging biomarker discovery and validation approach due to its sensitivity in capturing changes and reflecting on...
5.
Phat N, Tien N, Anh N, Yen N, Lee Y, Trinh H, et al.
Front Immunol
. 2023 Nov;
14:1210372.
PMID: 38022579
Background: The optimal diagnosis and treatment of tuberculosis (TB) are challenging due to underdiagnosis and inadequate treatment monitoring. Lipid-related genes are crucial components of the host immune response in TB....
6.
Yen N, Phat N, Oh J, Park S, Moon K, Thu V, et al.
Toxicol Appl Pharmacol
. 2023 Jun;
473:116597.
PMID: 37321324
Tacrolimus (TAC)-based treatment is associated with nephrotoxicity and hepatotoxicity; however, the underlying molecular mechanisms responsible for this toxicity have not been fully explored. This study elucidated the molecular processes underlying...
7.
Yen N, Anh N, Jayanti R, Phat N, Vu D, Ghim J, et al.
Biochimie
. 2023 Apr;
211:153-163.
PMID: 37062470
Type 2 diabetes mellitus (DM) poses a major burden for the treatment and control of tuberculosis (TB). Characterization of the underlying metabolic perturbations in DM patients with TB infection would...
8.
Anh N, Phat N, Yen N, Jayanti R, Thu V, Park Y, et al.
Biomed Pharmacother
. 2023 Mar;
158:114187.
PMID: 36916440
In this study, we investigated the lipidome of tuberculosis patients during standard chemotherapy to discover biosignatures that could aid therapeutic monitoring. UPLC-QToF MS was used to analyze 82 baseline and...
9.
Soedarsono S, Jayanti R, Mertaniasih N, Kusmiati T, Permatasari A, Indrawanto D, et al.
Tuberculosis (Edinb)
. 2023 Feb;
139:102325.
PMID: 36841141
Background: Interindividual variability in the pharmacokinetics (PK) of anti-tuberculosis (TB) drugs is the leading cause of treatment failure. Herein, we evaluated the influence of demographic, clinical, and genetic factors that...
10.
Long N, Anh N, Yen N, Phat N, Park S, Thu V, et al.
Sci Rep
. 2022 Aug;
12(1):13395.
PMID: 35927287
Despite remarkable success in the prevention and treatment of tuberculosis (TB), it remains one of the most devastating infectious diseases worldwide. Management of TB requires an efficient and timely diagnostic...