Ngalle Eric Mbua
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Explore the profile of Ngalle Eric Mbua including associated specialties, affiliations and a list of published articles.
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7
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262
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Recent Articles
1.
Arumugam S, Guo J, Mbua N, Friscourt F, Lin N, Nekongo E, et al.
Chem Sci
. 2014 Apr;
5(4):1591-1598.
PMID: 24765521
Selective derivatization of solvent-exposed cysteine residues in peptides and proteins is achieved by brief irradiation of an aqueous solution containing 3-(hydroxymethyl)-2-naphthol derivatives (NQMPs) with 350 nm fluorescent lamp. NQMP can...
2.
Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I
Mbua N, Li X, Flanagan-Steet H, Meng L, Aoki K, Moremen K, et al.
Angew Chem Int Ed Engl
. 2013 Oct;
52(49):13012-5.
PMID: 24129959
A game of tag: N-Glycans on the surface of living cells were selectively tagged by exogenously administering recombinant ST6Gal I sialyltransferase and azide-modified CMP-Neu5Ac. This modification was followed by a...
3.
Mbua N, Flanagan-Steet H, Johnson S, Wolfert M, Boons G, Steet R
Proc Natl Acad Sci U S A
. 2013 Jun;
110(25):10207-12.
PMID: 23733943
Niemann-Pick type C (NPC) disease is characterized by impaired cholesterol efflux from late endosomes and lysosomes and secondary accumulation of lipids. Although impaired trafficking of individual glycoproteins and glycolipids has...
4.
Friscourt F, Ledin P, Mbua N, Flanagan-Steet H, Wolfert M, Steet R, et al.
J Am Chem Soc
. 2012 Mar;
134(11):5381-9.
PMID: 22376061
Although strain-promoted alkyne-azide cycloadditions (SPAAC) have found wide utility in biological and material sciences, the low polarity and limited water solubility of commonly used cyclooctynes represent a serious shortcoming. To...
5.
Mbua N, Guo J, Wolfert M, Steet R, Boons G
Chembiochem
. 2011 Jun;
12(12):1912-21.
PMID: 21661087
We have shown that 4-dibenzocyclooctynol (DIBO), which can easily be obtained by a streamlined synthesis approach, reacts exceptionally fast in the absence of a Cu(I) catalyst with azido-containing compounds to...
6.
Sanders B, Friscourt F, Ledin P, Mbua N, Arumugam S, Guo J, et al.
J Am Chem Soc
. 2010 Dec;
133(4):949-57.
PMID: 21182329
Although metal-free cycloadditions of cyclooctynes and azides to give stable 1,2,3-triazoles have found wide utility in chemical biology and material sciences, there is an urgent need for faster and more...
7.
Poloukhtine A, Mbua N, Wolfert M, Boons G, Popik V
J Am Chem Soc
. 2009 Oct;
131(43):15769-76.
PMID: 19860481
Phototriggering of the metal-free azide to acetylene cycloaddition reaction was achieved by masking the triple bond of dibenzocyclooctynes as cyclopropenone. Such masked cyclooctynes do not react with azides in the...