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Neus Pedraza

Explore the profile of Neus Pedraza including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 230
Followers 0
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Recent Articles
1.
Lorite N, Apostolova S, Guasch-Valles M, Pryer A, Unzueta F, Freire R, et al.
Cell Mol Life Sci . 2024 Jun; 81(1):251. PMID: 38847937
The Smc5/6 complex is a highly conserved molecular machine involved in the maintenance of genome integrity. While its functions largely depend on restraining the fork remodeling activity of Mph1 in...
2.
Pedraza N, Monserrat M, Ferrezuelo F, Torres-Rosell J, Colomina N, Miguez-Cabello F, et al.
Cell Mol Life Sci . 2023 Sep; 80(10):280. PMID: 37684532
Nuclear Cyclin D1 (Ccnd1) is a main regulator of cell cycle progression and cell proliferation. Interestingly, Ccnd1 moves to the cytoplasm at the onset of differentiation in neuronal precursors. However,...
3.
Matas-Nadal C, Bech-Serra J, Gatius S, Gomez X, Ribes-Santolaria M, Guasch-Valles M, et al.
Mol Cell Proteomics . 2023 Apr; 22(6):100547. PMID: 37059366
Basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (SCCs) are the most frequent types of cancer, and both originate from the keratinocyte transformation, giving rise to the group of...
4.
Cemeli T, Guasch-Valles M, Ribes-Santolaria M, Ibars E, Navaridas R, Dolcet X, et al.
Int J Mol Sci . 2022 Jul; 23(15). PMID: 35897776
Glioblastoma (GBM) is the most common tumor in the central nervous system in adults. This neoplasia shows a high capacity of growth and spreading to the surrounding brain tissue, hindering...
5.
Bozic M, Caus M, Rodrigues-Diez R, Pedraza N, Ruiz-Ortega M, Gari E, et al.
Nat Commun . 2020 Apr; 11(1):1943. PMID: 32327648
Kidney fibrosis is a highly deleterious process and a final manifestation of chronic kidney disease. Alpha-(α)-synuclein (SNCA) is an actin-binding neuronal protein with various functions within the brain; however, its...
6.
Cemeli T, Guasch-Valles M, Nager M, Felip I, Cambray S, Santacana M, et al.
J Pathol . 2019 Apr; 248(4):501-513. PMID: 30957234
Glioblastoma (GBM) is a highly invasive brain neoplasia with an elevated recurrence rate after surgical resection. The cyclin D1 (Ccnd1)/Cdk4-retinoblastoma 1 (RB1) axis is frequently altered in GBM, leading to...
7.
Ortiz R, Georgieva M, Gutierrez S, Pedraza N, Fernandez-Moya S, Gallego C
Cell Rep . 2017 Jul; 20(1):13-20. PMID: 28683307
Regulation of mRNA localization is a conserved cellular process observed in many types of cells and organisms. Asymmetrical mRNA distribution plays a particularly important role in the nervous system, where...
8.
Pedraza N, Cemeli T, Monserrat M, Gari E, Ferrezuelo F
Small GTPases . 2017 Jan; 10(1):47-53. PMID: 28129038
Together with a cyclin-dependent kinase (CDK) partner G1 cyclins control cell cycle entry by phosphorylating a number of nuclear targets and releasing a transcriptional program at the end of G1...
9.
Fuste N, Fernandez-Hernandez R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al.
Nat Commun . 2016 May; 7:11581. PMID: 27181366
Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression promotes tumour growth and metastasis. While...
10.
Fuste N, Castelblanco E, Felip I, Santacana M, Fernandez-Hernandez R, Gatius S, et al.
Oncotarget . 2016 Apr; 7(19):26979-91. PMID: 27105504
Cyclin D1 (Ccnd1) is a proto-oncogen amplified in many different cancers and nuclear accumulation of Ccnd1 is a characteristic of tumor cells. Ccnd1 activates the transcription of a large set...