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Nestor Parga

Explore the profile of Nestor Parga including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 946
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Recent Articles
1.
Serrano-Fernandez L, Beiran M, Romo R, Parga N
Proc Natl Acad Sci U S A . 2024 Dec; 121(50):e2312831121. PMID: 39636858
Perception is influenced by sensory stimulation, prior knowledge, and contextual cues, which collectively contribute to the emergence of perceptual biases. However, the precise neural mechanisms underlying these biases remain poorly...
2.
Serrano-Fernandez L, Beiran M, Parga N
Cell Rep . 2024 Jul; 43(7):114412. PMID: 38968075
A stimulus held in working memory is perceived as contracted toward the average stimulus. This contraction bias has been extensively studied in psychophysics, but little is known about its origin...
3.
Sarno S, Beiran M, Falco-Roget J, Diaz-deLeon G, Rossi-Pool R, Romo R, et al.
Proc Natl Acad Sci U S A . 2022 Jan; 119(2). PMID: 34992139
Little is known about how dopamine (DA) neuron firing rates behave in cognitively demanding decision-making tasks. Here, we investigated midbrain DA activity in monkeys performing a discrimination task in which...
4.
Perez-Zabalza M, Reig R, Manrique J, Jercog D, Winograd M, Parga N, et al.
J Physiol . 2020 May; 598(16):3439-3457. PMID: 32406934
Key Points: We confirm that GABA receptors (GABA -Rs) are involved in the termination of Up-states; their blockade consistently elongates Up-states. GABA -Rs also modulate Down-states and the oscillatory cycle,...
5.
Sarno S, de Lafuente V, Romo R, Parga N
Proc Natl Acad Sci U S A . 2017 Nov; 114(48):E10494-E10503. PMID: 29133424
Learning to associate unambiguous sensory cues with rewarded choices is known to be mediated by dopamine (DA) neurons. However, little is known about how these neurons behave when choices rely...
6.
Rossi-Pool R, Salinas E, Zainos A, Alvarez M, Vergara J, Parga N, et al.
Proc Natl Acad Sci U S A . 2016 Nov; 113(49):E7966-E7975. PMID: 27872293
The problem of neural coding in perceptual decision making revolves around two fundamental questions: (i) How are the neural representations of sensory stimuli related to perception, and (ii) what attributes...
7.
Carnevale F, de Lafuente V, Romo R, Barak O, Parga N
Neuron . 2015 May; 86(4):1067-1077. PMID: 25959731
Under uncertainty, the brain uses previous knowledge to transform sensory inputs into the percepts on which decisions are based. When the uncertainty lies in the timing of sensory evidence, however,...
8.
Carnevale F, de Lafuente V, Romo R, Parga N
Neuron . 2013 Nov; 80(6):1532-43. PMID: 24268419
Decisions emerge from the concerted activity of neuronal populations distributed across brain circuits. However, the analytical tools best suited to decode decision signals from neuronal populations remain unknown. Here we...
9.
Carnevale F, de Lafuente V, Romo R, Parga N
Proc Natl Acad Sci U S A . 2012 Nov; 109(46):18938-43. PMID: 23112203
In perceptual decision-making tasks the activity of neurons in frontal and posterior parietal cortices covaries more with perceptual reports than with the physical properties of stimuli. This relationship is revealed...
10.
Renart A, de la Rocha J, Bartho P, Hollender L, Parga N, Reyes A, et al.
Science . 2010 Jan; 327(5965):587-90. PMID: 20110507
Correlated spiking is often observed in cortical circuits, but its functional role is controversial. It is believed that correlations are a consequence of shared inputs between nearby neurons and could...