Nelson Lopez-Sejas
Overview
Explore the profile of Nelson Lopez-Sejas including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
287
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Recent Articles
1.
Carreira-Santos S, Lopez-Sejas N, Gonzalez-Sanchez M, Sanchez-Hernandez E, Pera A, Hassouneh F, et al.
Front Immunol
. 2023 Nov;
14:1256404.
PMID: 37908353
Introduction: Natural killer (NK) cells are a key component of the innate immune system, involved in defending the host against virus-infected cells and tumor immunosurveillance. Under culture conditions, IL-12/15/18 can...
2.
Formentini M, Navas A, Hassouneh F, Lopez-Sejas N, Alonso C, Tarazona R, et al.
J Gerontol A Biol Sci Med Sci
. 2021 May;
76(11):1946-1953.
PMID: 33993242
Immunosenescence affects innate and adaptive immunity impairing the response to pathogens and vaccines. Chronic infection with cytomegalovirus (CMV) has been shown to drive "early immunosenescence" and can considerably affect both...
3.
Valhondo I, Hassouneh F, Lopez-Sejas N, Pera A, Sanchez-Correa B, Guerrero B, et al.
Cancers (Basel)
. 2020 Aug;
12(8).
PMID: 32764229
: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with...
4.
Tarazona R, Lopez-Sejas N, Guerrero B, Hassouneh F, Valhondo I, Pera A, et al.
Cancer Immunol Immunother
. 2020 Mar;
69(5):879-899.
PMID: 32130453
A better understanding of the complex interactions between the immune system and tumour cells from different origins has opened the possibility to design novel procedures of antitumoral immunotherapy. One of...
5.
Almeida J, Couceiro P, Lopez-Sejas N, Alves V, Ruzickova L, Tarazona R, et al.
Front Immunol
. 2019 Nov;
10:2493.
PMID: 31695700
Therapy with Tyrosine Kinase Inhibitors (TKI) aiming stable deep molecular response is the gold standard to treat Chronic Myeloid Leukemia (CML). NKT-like cells (CD3CD56) combine characteristics of T and NK...
6.
Sanchez-Correa B, Valhondo I, Hassouneh F, Lopez-Sejas N, Pera A, Bergua J, et al.
Cancers (Basel)
. 2019 Jun;
11(6).
PMID: 31234588
Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance...
7.
Sanchez-Correa B, Lopez-Sejas N, Duran E, Labella F, Alonso C, Solana R, et al.
Cancer Immunol Immunother
. 2019 Apr;
68(5):861-870.
PMID: 30953117
The incidence of some types of tumours has increased progressively in recent years and is expected to continue growing in the coming years due in part to the aging of...
8.
Rodrigues-Santos P, Lopez-Sejas N, Almeida J, Ruzickova L, Couceiro P, Alves V, et al.
Front Immunol
. 2018 Nov;
9:2587.
PMID: 30487792
Natural killer (NK) cells are a very important component of the innate immune response involved in the lysis of virus infected and tumor cells. Aging has a profound impact in...
9.
Hassouneh F, Lopez-Sejas N, Campos C, Sanchez-Correa B, Tarazona R, Pera A, et al.
Int J Mol Sci
. 2017 Jun;
18(7).
PMID: 28661443
The differential impact of ageing and cytomegalovirus (CMV) latent infection on human T-cell subsets remains to some extent controversial. The purpose of this study was to analyse the expression of...
10.
Hassouneh F, Lopez-Sejas N, Campos C, Sanchez-Correa B, Tarazona R, Solana R, et al.
Front Immunol
. 2017 Jun;
8:649.
PMID: 28626460
Immunosenescence is a progressive deterioration of the immune system with aging. It affects both innate and adaptive immunity limiting the response to pathogens and to vaccines. As chronic cytomegalovirus (CMV)...