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Nellie Dumont

Explore the profile of Nellie Dumont including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 29
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Recent Articles
1.
Manesia J, Maganti H, Almoflehi S, Jahan S, Hasan T, Pasha R, et al.
Cell Rep Methods . 2023 Dec; 3(12):100663. PMID: 38070507
Small molecules have enabled expansion of hematopoietic stem and progenitor cells (HSPCs), but limited knowledge is available on whether these agonists can act synergistically. In this work, we identify a...
2.
Boccacci Y, Dumont N, Doyon Y, Laganiere J
Cytotherapy . 2023 Aug; 25(11):1242-1248. PMID: 37598334
Background Aims: The culture and ex vivo engineering of red blood cells (RBCs) can help characterize genetic variants, model diseases, and may eventually spur the development of applications in transfusion...
3.
Dumont N, Boyer L, Emond H, Celebi-Saltik B, Pasha R, Bazin R, et al.
Exp Hematol . 2014 May; 42(9):741-52.e1. PMID: 24793546
Strategies to enhance the expansion of umbilical cord blood hematopoietic stem and progenitor cells (HSPCs) are crucial to enable their widespread application to adults and to overcome important limitations, such...
4.
Neron S, Roy A, Dumont N
PLoS One . 2013 Jan; 7(12):e51946. PMID: 23284827
Polyclonal preparations of therapeutic immunoglobulins, namely intravenous immunoglobulins (IVIg), are essential in the treatment of immunodeficiency and are increasingly used for the treatment of autoimmune and inflammatory diseases. Currently, patients'...
5.
Tounkara F, Dumont N, Fournier S, Boyer L, Nadeau P, Pineault N
Stem Cells Dev . 2012 May; 21(17):3197-208. PMID: 22564002
Hyperthermia treatment has at times been associated with increased platelet levels in humans. The heat shock protein HSP70, which can be induced by hyperthermia in megakaryocytes and erythrocytes, was recently...
6.
Cayer M, Samson M, Bertrand C, Dumont N, Drouin M, Jung D
J Immunol Methods . 2012 Jan; 376(1-2):113-24. PMID: 22210093
Investigation of the molecular processes which control the development and function of lymphocytes is essential for our understanding of humoral immunity, as well as lymphocyte associated pathogenesis. Adenovirus-mediated gene transfer...
7.
Neron S, Roy A, Dumont N, Dussault N
J Immunol Methods . 2011 Jul; 371(1-2):61-9. PMID: 21723869
CD40-CD154 interaction is used to culture human B lymphocytes, which are now viewed as effectors to potentially promote T lymphocyte response against malignant cells in cell-based therapy. Currently, the media...
8.
Ducas E, Dussault N, Roy A, Dumont N, Neron S
J Immunol Methods . 2009 Apr; 344(2):133-7. PMID: 19332074
The CD40-CD154 interaction is better exemplified by a rheostat than by an on-off switch, and variations in its intensity can play a role in the regulation of B lymphocyte activation...
9.
Dumont N, Aubin E, Proulx D, Lemieux R, Bazin R
Immunology . 2008 Sep; 126(4):588-95. PMID: 18778289
Human B cells can be cultured ex vivo for a few weeks, following stimulation of the CD40 cell surface molecule in the presence of recombinant cytokines such as interleukin-4 (IL-4)....