Nele Tamberg
Overview
Explore the profile of Nele Tamberg including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
441
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Recent Articles
1.
Eickhoff P, Kose H, Martino F, Petojevic T, Abid Ali F, Locke J, et al.
Cell Rep
. 2019 Sep;
28(10):2673-2688.e8.
PMID: 31484077
In the eukaryotic replisome, DNA unwinding by the Cdc45-MCM-Go-Ichi-Ni-San (GINS) (CMG) helicase requires a hexameric ring-shaped ATPase named minichromosome maintenance (MCM), which spools single-stranded DNA through its central channel. Not...
2.
Tamberg N, Tahk S, Koit S, Kristjuhan K, Kasvandik S, Kristjuhan A, et al.
Sci Rep
. 2018 Aug;
8(1):12136.
PMID: 30108253
Coordination of DNA replication and cellular redox homeostasis mechanisms is essential for the sustained genome stability due to the sensitivity of replicating DNA to oxidation. However, substantial gaps remain in...
3.
Saul S, Ferguson M, Cordonin C, Fragkoudis R, Ool M, Tamberg N, et al.
J Virol
. 2015 Aug;
89(21):11030-45.
PMID: 26311875
Unlabelled: The A7(74) strain of Semliki Forest virus (SFV; genus Alphavirus) is avirulent in adult mice, while the L10 strain is virulent in mice of all ages. It has been...
4.
Ilves I, Tamberg N, Botchan M
Proc Natl Acad Sci U S A
. 2012 Aug;
109(33):13163-70.
PMID: 22853956
The replication of eukaryote chromosomes slows down when DNA is damaged and the proteins that work at the fork (the replisome) are known targets for the signaling pathways that mediate...
5.
Balamotis M, Tamberg N, Woo Y, Li J, Davy B, Kohwi-Shigematsu T, et al.
Mol Cell Biol
. 2011 Nov;
32(2):333-47.
PMID: 22064485
Complex behaviors, such as learning and memory, are associated with rapid changes in gene expression of neurons and subsequent formation of new synaptic connections. However, how external signals are processed...
6.
Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan M, et al.
Nat Struct Mol Biol
. 2011 Mar;
18(4):471-7.
PMID: 21378962
Two central steps for initiating eukaryotic DNA replication involve loading of the Mcm2-7 helicase onto double-stranded DNA and its activation by GINS-Cdc45. To better understand these events, we determined the...
7.
Fragkoudis R, Tamberg N, Siu R, Kiiver K, Kohl A, Merits A, et al.
J Neurovirol
. 2008 Dec;
15(1):57-70.
PMID: 19115134
Semliki Forest virus (SFV) provides an experimental model of acute virus encephalitis and virus-induced demyelinating disease. Two marker viruses expressing fluorescent proteins as part of the replicase or the structural...
8.
Kiiver K, Tagen I, Zusinaite E, Tamberg N, Fazakerley J, Merits A
J Gen Virol
. 2008 May;
89(Pt 6):1457-1466.
PMID: 18474562
Semliki Forest virus (SFV) non-structural protein 1 (nsP1) is a major component of the virus replicase complex. It has previously been studied in cells infected with virus or using transient...
9.
Tamberg N, Lulla V, Fragkoudis R, Lulla A, Fazakerley J, Merits A
J Gen Virol
. 2007 Mar;
88(Pt 4):1225-1230.
PMID: 17374766
Alphavirus-based vector and replicon systems have been extensively used experimentally and are likely to be used in human and animal medicine. Whilst marker genes can be inserted easily under the...