Nela Pragathi Sneha
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Explore the profile of Nela Pragathi Sneha including associated specialties, affiliations and a list of published articles.
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4
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5
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Recent Articles
1.
Sneha N, Dharshini S, Taguchi Y, Gromiha M
Genes (Basel)
. 2024 Nov;
15(11).
PMID: 39596631
Background/objectives: Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disorder characterized by the loss of upper and lower motor neurons. Key factors contributing to neuronal death include mitochondrial energy damage, oxidative...
2.
Sneha N, Dharshini S, Taguchi Y, Gromiha M
Genes (Basel)
. 2023 Sep;
14(9).
PMID: 37761940
Huntington's disease (HD) is a progressive neurodegenerative disorder caused due to a CAG repeat expansion in the huntingtin () gene. The primary symptoms of HD include motor dysfunction such as...
3.
Sneha N, Dharshini S, Taguchi Y, Gromiha M
Genes (Basel)
. 2022 Dec;
13(12).
PMID: 36553652
Huntington's disease (HD) is a neurodegenerative disorder with autosomal dominant inheritance caused by glutamine expansion in the Huntingtin gene (HTT). Striatal projection neurons (SPNs) in HD are more vulnerable to...
4.
Dharshini S, Sneha N, Yesudhas D, Kulandaisamy A, Rangaswamy U, Shanmugam A, et al.
Curr Top Med Chem
. 2022 Sep;
22(22):1868-1879.
PMID: 36056872
The progressive deterioration of neurons leads to Alzheimer's disease (AD), and developing a drug for this disorder is challenging. Substantial gene/transcriptome variability from multiple cell types leads to downstream pathophysiologic...