Neil Gozzard
Overview
Explore the profile of Neil Gozzard including associated specialties, affiliations and a list of published articles.
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10
Citations
141
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Recent Articles
1.
Hayes A, Rane S, Scales H, Meehan G, Benson R, Maroof A, et al.
Front Immunol
. 2019 Apr;
10:598.
PMID: 31024523
Initiation of adaptive immunity involves distinct migratory cell populations coming together in a highly dynamic and spatially organized process. However, we lack a detailed spatiotemporal map of these events due...
2.
Lightwood D, ODowd V, Carrington B, Veverka V, Carr M, Tservistas M, et al.
J Mol Biol
. 2018 Jun;
425(11):2082.
PMID: 29890570
No abstract available.
3.
Lightwood D, Tservistas M, Zehentleitner M, Sarkar K, Turner A, Bracher M, et al.
Am J Respir Crit Care Med
. 2018 Jun;
198(5):610-619.
PMID: 29883204
Rationale: IL-13 is an important cytokine implicated in the pathogenesis of allergic asthma and is an attractive target for an inhaled therapeutic. Objective: To investigate the efficacy of CDP7766, a...
4.
Cope A, Barnes M, Belson A, Binks M, Brockbank S, Bonachela-Capdevila F, et al.
Nat Rev Rheumatol
. 2018 Jan;
14(2):119.
PMID: 29362468
This corrects the article DOI: 10.1038/nrrheum.2017.200.
5.
Cope A, Barnes M, Belson A, Binks M, Brockbank S, Bonachela-Capdevila F, et al.
Nat Rev Rheumatol
. 2017 Dec;
14(1):53-60.
PMID: 29213124
Collaboration can be challenging; nevertheless, the emerging successes of large, multi-partner, multi-national cooperatives and research networks in the biomedical sector have sustained the appetite of academics and industry partners for...
6.
Singhania A, Rupani H, Jayasekera N, Lumb S, Hales P, Gozzard N, et al.
PLoS One
. 2017 Jan;
12(1):e0168680.
PMID: 28045928
Management of severe asthma remains a challenge despite treatment with glucocorticosteroid therapy. The majority of studies investigating disease mechanisms in treatment-resistant severe asthma have previously focused on the large central...
7.
De Alba J, Otal R, Calama E, Domenech A, Prats N, Gozzard N, et al.
Clin Sci (Lond)
. 2015 Aug;
129(11):973-87.
PMID: 26245201
RNA viruses are a major cause of respiratory infections and are known to exacerbate asthma and other respiratory diseases. Our aim was to test the ability of poly(I:C) (polyinosinic:polycytidylic acid),...
8.
Hardyman M, Wilkinson E, Martin E, Jayasekera N, Blume C, Swindle E, et al.
J Allergy Clin Immunol
. 2013 May;
132(3):665-675.e8.
PMID: 23632299
Background: Because TNF-α is increased in severe asthma, we hypothesized that TNF-α contributes to barrier dysfunction and cell activation in bronchial epithelial cells. We further hypothesized that src-family kinase inhibition...
9.
Lightwood D, ODowd V, Carrington B, Veverka V, Carr M, Tservistas M, et al.
J Mol Biol
. 2012 Dec;
425(3):577-93.
PMID: 23219467
We describe the discovery, engineering and characterisation of a highly potent anti-human interleukin (IL)-13 Fab fragment designed for administration by inhalation. The lead candidate molecule was generated via a novel...
10.
Babu S, Puddicombe S, Arshad H, Wilson S, Ward J, Gozzard N, et al.
Clin Immunol
. 2011 Apr;
140(1):18-25.
PMID: 21459047
Subjects with mild asthma underwent repeated low-dose allergen exposure and bronchial biopsies were examined for the expression of TNF-α and adhesion molecules. Bronchial biopsies from moderately severe asthmatics were then...