Nefeli Zacharopoulou
Overview
Explore the profile of Nefeli Zacharopoulou including associated specialties, affiliations and a list of published articles.
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12
Citations
131
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Recent Articles
1.
Hosseinzadeh Z, Hauser S, Singh Y, Pelzl L, Schuster S, Sharma Y, et al.
Sci Rep
. 2020 May;
10(1):8391.
PMID: 32439941
Loss of function mutations of the chorein-encoding gene VPS13A lead to chorea-acanthocytosis (ChAc), a neurodegenerative disorder with accelerated suicidal neuronal cell death, which could be reversed by lithium. Chorein upregulates...
2.
Kallergi G, Hoffmann O, Bittner A, Papadimitriou L, Katsarou S, Zacharopoulou N, et al.
Ther Adv Med Oncol
. 2020 May;
12:1758835919895754.
PMID: 32426042
Background: The chemokine receptor CXCR4 and the transcription factor JUNB, expressed on a variety of tumor cells, seem to play an important role in the metastatic process. Since disseminated tumor...
3.
Zacharopoulou N, Kallergi G, Alkahtani S, Tsapara A, Alarifi S, Schmid E, et al.
Cancer Biol Ther
. 2020 Mar;
21(6):533-540.
PMID: 32175798
Recent studies revealed that the histone demethylase KDM2B regulates the epithelial markers E-Cadherin and ZO-1, the RhoA/B/C-small-GTPases and actin cytoskeleton organization, in DU-145 prostate- and HCT-116 colon-tumor cells. Here we...
4.
Kallergi G, Tsintari V, Sfakianakis S, Bei E, Lagoudaki E, Koutsopoulos A, et al.
Breast Cancer Res
. 2019 Aug;
21(1):86.
PMID: 31370904
Background: Circulating tumor cells (CTCs) are important for metastatic dissemination of cancer. They can provide useful information, regarding biological features and tumor heterogeneity; however, their detection and characterization are difficult...
5.
Lang F, Stournaras C, Zacharopoulou N, Voelkl J, Alesutan I
Cell Stress
. 2019 Jun;
3(1):1-8.
PMID: 31225494
Expression of the serum- and glucocorticoid-inducible kinase 1 (SGK1) is up-regulated by several types of cell stress, such as ischemia, radiation and hyperosmotic shock. The SGK1 protein is activated by...
6.
Abdelazeem K, Droppova B, Sukkar B, Al-Maghout T, Pelzl L, Zacharopoulou N, et al.
Biochem Biophys Res Commun
. 2019 Mar;
512(3):467-472.
PMID: 30902388
Placental growth factor (PlGF) is produced by tumor cells and stimulates tumor growth and metastasis in part by upregulation of hypoxia inducible factor HIF1α. Orchestration of tumor cell proliferation and...
7.
Fink M, Mamun Bhuyan A, Zacharopoulou N, Lang F
Cell Physiol Biochem
. 2018 Nov;
51(2):501-512.
PMID: 30458445
Background/aims: The taurine derivative Taurolidine is effective against diverse bacteria and tumor growth. In the treatment of cancer, the substance is effective in part by triggering suicidal death or apoptosis...
8.
Sukkar B, Hauser S, Pelzl L, Hosseinzadeh Z, Sahu I, Al-Maghout T, et al.
Cell Physiol Biochem
. 2018 Nov;
51(1):278-289.
PMID: 30453283
Background/aims: The neurodegenerative disease Chorea-Acanthocytosis (ChAc) is caused by loss-of-function-mutations of the chorein-encoding gene VPS13A. In ChAc neurons transcript levels and protein abundance of Ca2+ release activated channel moiety (CRAC)...
9.
Fink M, Mamun Bhuyan A, Zacharopoulou N, Lang F
Cell Physiol Biochem
. 2018 Nov;
50(6):2283-2295.
PMID: 30423572
Background/aims: The sesquiterpene lactone Costunolide is effective against various disorders including inflammation and malignancy. The substance is effective in part by triggering suicidal death or apoptosis of tumor cells. Mechanisms...
10.
Zacharopoulou N, Tsapara A, Kallergi G, Schmid E, Alkahtani S, Alarifi S, et al.
Cell Physiol Biochem
. 2018 May;
47(1):368-377.
PMID: 29772566
Background/aims: The epigenetic factor KDM2B is a histone demethylase expressed in various tumors. Recently, we have shown that KDM2B regulates actin cytoskeleton organization, small Rho GTPases signaling, cell-cell adhesion and...