Neelima Sukumar
Overview
Explore the profile of Neelima Sukumar including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
493
Followers
0
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Recent Articles
1.
Jiang T, Edwards N, Sukumar N, Mayers M, Higgins J, Kosanam H
J Chromatogr B Analyt Technol Biomed Life Sci
. 2023 Jan;
1215:123589.
PMID: 36592589
Pepstatin A reversibly inhibits aspartic acid proteases and minimizes the impact of protease-induced degradation in recombinant protein manufacturing process. Pepstatin A is considered as a process-related impurity and must be...
2.
Nazarova E, Montague C, La T, Wilburn K, Sukumar N, Lee W, et al.
Elife
. 2017 Jul;
6.
PMID: 28708968
Pathogenic bacteria have evolved highly specialized systems to extract essential nutrients from their hosts. (Mtb) scavenges lipids (cholesterol and fatty acids) to maintain infections in mammals but mechanisms and proteins...
3.
Nicholson T, Brockmeier S, Sukumar N, Paharik A, Lister J, Horswill A, et al.
Infect Immun
. 2017 Jun;
85(8).
PMID: 28559403
is pervasive in swine populations and plays multiple roles in respiratory disease. Additionally, is capable of establishing long-term or chronic infections in swine. Bacterial biofilms are increasingly recognized as important...
4.
McCormack R, de Armas L, Shiratsuchi M, Fiorentino D, Olsson M, Lichtenheld M, et al.
Elife
. 2015 Sep;
4.
PMID: 26402460
Perforin-2 (MPEG1) is a pore-forming, antibacterial protein with broad-spectrum activity. Perforin-2 is expressed constitutively in phagocytes and inducibly in parenchymal, tissue-forming cells. In vitro, Perforin-2 prevents the intracellular replication and...
5.
Russell D, Lee W, Tan S, Sukumar N, Podinovskaia M, Fahey R, et al.
Microbiol Spectr
. 2015 Jan;
2(5).
PMID: 25584198
Mycobacterium tuberculosis is an incredibly successful pathogen with an extraordinary penetrance of its target host population. The ability to infect many yet cause disease in few is undoubtedly central to...
6.
Sukumar N, Tan S, Aldridge B, Russell D
PLoS Pathog
. 2014 Sep;
10(9):e1004394.
PMID: 25233380
Mycobacterium tuberculosis (Mtb) remains a major public health problem, with an effective vaccine continuing to prove elusive. Progress in vaccination strategies has been hampered by a lack of appreciation of...
7.
Sukumar N, Nicholson T, Conover M, Ganguly T, Deora R
Infect Immun
. 2014 Jan;
82(4):1627-37.
PMID: 24470470
Bordetella bronchiseptica is a Gram-negative bacterium that infects and causes disease in a wide variety of animals. B. bronchiseptica also infects humans, thereby demonstrating zoonotic transmission. An extensive characterization of...
8.
Tan S, Sukumar N, Abramovitch R, Parish T, Russell D
PLoS Pathog
. 2013 Apr;
9(4):e1003282.
PMID: 23592993
The ability of Mycobacterium tuberculosis (Mtb) to thrive in its phagosomal niche is critical for its establishment of a chronic infection. This requires that Mtb senses and responds to intraphagosomal...
9.
Conover M, Redfern C, Ganguly T, Sukumar N, Sloan G, Mishra M, et al.
J Bacteriol
. 2011 Nov;
194(2):233-42.
PMID: 22056934
Bordetella bacteria are Gram-negative respiratory pathogens of animals, birds, and humans. A hallmark feature of some Bordetella species is their ability to efficiently survive in the respiratory tract even after...
10.
Conover M, Sloan G, Love C, Sukumar N, Deora R
Mol Microbiol
. 2010 Jul;
77(6):1439-55.
PMID: 20633227
Many respiratory pathogens establish persistent infection or a carrier state in the human nasopharynx without overt disease symptoms but the presence of these in the lungs usually results in disease....