Neda Moradin
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Explore the profile of Neda Moradin including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
216
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Recent Articles
1.
Corbett R, Eveleigh R, Whitney J, Barai N, Bourgey M, Chuah E, et al.
Front Genet
. 2020 Dec;
11:612515.
PMID: 33335541
Population sequencing often requires collaboration across a distributed network of sequencing centers for the timely processing of thousands of samples. In such massive efforts, it is important that participating scientists...
2.
Xu G, van Bruggen R, Gualtieri C, Moradin N, Fois A, Vallerand D, et al.
Cell Rep
. 2020 Sep;
32(12):108170.
PMID: 32966787
The replication cycle and pathogenesis of the Plasmodium malarial parasite involves rapid expansion in red blood cells (RBCs), and variants of certain RBC-specific proteins protect against malaria in humans. In...
3.
Langlais D, Cencic R, Moradin N, Kennedy J, Ayi K, Brown L, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(10):E2366-E2375.
PMID: 29463745
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by parasites that is associated with high rates of mortality and morbidity. Treatment options are currently few, and...
4.
Fodil N, Moradin N, Leung V, Olivier J, Radovanovic I, Jeyakumar T, et al.
Nat Commun
. 2017 Oct;
8(1):932.
PMID: 29030607
Inflammatory bowel disease (IBD) involves interaction between host genetic factors and environmental triggers. CCDC88B maps within one IBD risk locus on human chromosome 11q13. Here we show that CCDC88B protein...
5.
Matte C, Casgrain P, Seguin O, Moradin N, Hong W, Descoteaux A
PLoS Pathog
. 2016 Jun;
12(6):e1005690.
PMID: 27280768
The protozoan Leishmania parasitizes macrophages and evades the microbicidal consequences of phagocytosis through the inhibition of phagolysosome biogenesis. In this study, we investigated the impact of this parasite on LC3-associated...
6.
Moradin N, Torre S, Gauthier S, Tam M, Hawari J, Vandercruyssen K, et al.
Malar J
. 2016 May;
15(1):260.
PMID: 27150250
Background: The potential emergence and spread of resistance to artemisinins in the Plasmodium falciparum malaria parasite constitutes a major global health threat. Hence, improving the efficacy of artemisinins and of...
7.
Matheoud D, Moradin N, Bellemare-Pelletier A, Shio M, Hong W, Olivier M, et al.
Cell Host Microbe
. 2013 Jul;
14(1):15-25.
PMID: 23870310
During phagocytosis, microorganisms are taken up by immune cells into phagosomes. Through membrane-trafficking events mediated by SNARE proteins, phagosomes fuse with lysosomes, generating degradative phagolysosomes. Phagolysosomes contribute to host immunity...
8.
Descoteaux A, Moradin N, Arango Duque G
Cell Host Microbe
. 2013 Mar;
13(3):245-7.
PMID: 23498949
Host lipid alterations are centrally involved in Leishmania donovani infection, and infected patients exhibit hypocholesterolemia. In this issue of Cell Host & Microbe, Ghosh et al. (2013) show that the...
9.
Moradin N, Descoteaux A
Front Cell Infect Microbiol
. 2012 Oct;
2:121.
PMID: 23050244
Upon their internalization by macrophages, Leishmania promastigotes inhibit phagolysosome biogenesis. The main factor responsible for this inhibition is the promastigote surface glycolipid lipophosphoglycan (LPG). This glycolipid has a profound impact...
10.
Bolhassani A, Gholami E, Zahedifard F, Moradin N, Parsi P, Doustdari F, et al.
Exp Parasitol
. 2011 Feb;
128(1):9-17.
PMID: 21276444
An intercellular spreading strategy using herpes simplex virus type 1 (HSV-1) VP22 protein is employed to enhance DNA vaccine potency of Leishmania major amastin antigen in BALB/c mice model. We...