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Neal X Chen

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Articles 75
Citations 2197
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Recent Articles
1.
Chen N, ONeill K, Wilson H, Srinivasan S, Bonewald L, Moe S
JBMR Plus . 2024 Dec; 9(1):ziae136. PMID: 39664935
Renal osteodystrophy (ROD) leads to increased fractures, potentially due to underlying low bone turnover in chronic kidney disease (CKD). We hypothesized that indoxyl sulfate (IS), a circulating toxin elevated in...
2.
Biruete A, Chen N, Metzger C, Srinivasan S, ONeill K, Fallen P, et al.
JBMR Plus . 2023 Dec; 7(12):e10837. PMID: 38130753
Chronic kidney disease (CKD)-mineral bone disorder (CKD-MBD) leads to fractures and cardiovascular disease. Observational studies suggest beneficial effects of dietary fiber on both bone and cardiovascular outcomes, but the effect...
3.
Narayanan G, Halim A, Hu A, Avin K, Lu T, Zehnder D, et al.
Kidney360 . 2023 Oct; 4(11):1562-1579. PMID: 37858297
No abstract available.
4.
Newman C, Surowiec R, Swallow E, Metzger C, Kim J, Tomaschke A, et al.
Bone . 2023 May; 173:116808. PMID: 37207990
Chronic kidney disease (CKD) is characterized by secondary hyperparathyroidism and an increased risk of hip fractures predominantly related to cortical porosity. Unfortunately, bone mineral density measurements and high-resolution peripheral computed...
5.
Biruete A, Chen N, Metzger C, Srinivasan S, Oa Neill K, Fallen P, et al.
bioRxiv . 2023 Feb; PMID: 36778372
Background: Dietary fiber is important for a healthy diet, but intake is low in CKD patients and the impact this has on the manifestations of CKD-Mineral Bone Disorder (MBD) is...
6.
Burstad K, Cladis D, Vorland C, Wastney M, Biruete A, Dominguez 2nd J, et al.
JBMR Plus . 2022 Dec; 6(12):e10698. PMID: 36530183
Dietary phosphorus restriction and phosphorus binders are commonly prescribed for patients with chronic kidney disease (CKD). However, occurrences of non-adherence to these interventions are common. As low-phosphorus (LP) diets have...
7.
Avin K, Dominguez 2nd J, Chen N, Hato T, Myslinski J, Gao H, et al.
J Orthop Res . 2022 Oct; 41(5):1060-1069. PMID: 36200412
Nonunion describes bone fractures that fail to heal, resulting in the fracture callus failing to fully ossify or, in atrophic cases, not forming altogether. Fracture healing is regulated, in part,...
8.
Metzger C, Newman C, Tippen S, Golemme N, Chen N, Moe S, et al.
Bone Rep . 2022 Aug; 17:101612. PMID: 36035656
Cortical porosity develops in chronic kidney disease (CKD) and increases with progressing disease. Cortical porosity is likely a prominent contributor to skeletal fragility/fracture. The degree to which cortical porosity occurs...
9.
Biruete A, Metzger C, Chen N, Swallow E, Vrabec C, Clinkenbeard E, et al.
Nephrol Dial Transplant . 2022 Apr; 37(10):1857-1867. PMID: 35482713
Background: Anemia and chronic kidney disease-mineral and bone disorder (CKD-MBD) are common and begin early in CKD. Limited studies have concurrently compared the effects of ferric citrate (FC) versus intravenous...
10.
Damrath J, Chen N, Metzger C, Srinivasan S, ONeill K, Biruete A, et al.
JBMR Plus . 2022 Mar; 6(3):e10600. PMID: 35309859
Chronic kidney disease-mineral and bone disorder (CKD-MBD) increases cardiovascular calcification and skeletal fragility in part by increasing systemic oxidative stress and disrupting mineral homeostasis through secondary hyperparathyroidism. We hypothesized that...