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Neal R Cutler

Explore the profile of Neal R Cutler including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 304
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Recent Articles
1.
Sramek J, Murphy M, Adcock S, Stark J, Cutler N
Rev Recent Clin Trials . 2021 Feb; 16(3):232-241. PMID: 33563172
Background: Phase 1 studies comprise the first exposure of a promising new chemical entity in healthy volunteers or, when appropriate, in patients. To assure a solid foundation for subsequent drug...
2.
Sramek J, Loebel A, Murphy M, Mao Y, Pikalov A, Cutler N
Prog Neuropsychopharmacol Biol Psychiatry . 2017 May; 78:12-17. PMID: 28499900
Background: Several studies have found that depressed, post-menopausal females may respond differently to antidepressants compared to pre-menopausal females. The atypical antipsychotic lurasidone, whose mechanism of action differs from SSRIs and...
3.
Sramek J, Murphy M, Cutler N
Dialogues Clin Neurosci . 2017 Feb; 18(4):447-457. PMID: 28179816
Although a number of studies have observed that females respond better to serotonergic antidepressants than males and that postmenopausal females have a diminished response to antidepressants compared with younger females,...
4.
Kittelson J, Steg P, Halperin J, Goldenberg N, Schulman S, Spyropoulos A, et al.
Thromb Haemost . 2016 Jun; 116(3):544-53. PMID: 27346176
Clinical trials of antithrombotic therapy require a cohesive assessment of benefit and risk. A new graphical method to represent the bivariate relation of benefit and risk in trials of antithrombotic...
5.
Sramek J, Hardy L, Bieck P, Zamora C, Versavel M, Kharidia J, et al.
CNS Neurosci Ther . 2016 Feb; 22(5):404-12. PMID: 26849844
Introduction: SEP-432 is a triple monoamine reuptake inhibitor of norepinephrine (NE), serotonin (5-HT), and dopamine (DA), based on in vitro binding studies. We sought evidence that SEP-432 engages these monoamine...
6.
Atiee G, Sramek J, Palasota J, Andrews S, Murphy M, Cutler N
J Neurol Sci . 2016 Jan; 360:131-2. PMID: 26723989
No abstract available.
7.
Sramek J, Andry J, Ding H, Riordan H, Leibowitz M, Cutler N
J Clin Psychopharmacol . 2013 Dec; 34(1):167-8. PMID: 24346745
No abstract available.
8.
Sramek J, Cutler N
Curr Top Behav Neurosci . 2011 Mar; 8:231-49. PMID: 21374019
There is a large body of literature debating whether and how gender affects the metabolism, side-effect profile, and efficacy of antidepressants. Gender differences in antidepressant pharmacokinetics and efficacy profiles have...
9.
Goldenberg N, Spyropoulos A, Halperin J, Kessler C, Schulman S, Turpie A, et al.
Blood . 2010 Nov; 117(7):2089-92. PMID: 21068436
Standards for clinical trial design, execution, and publication have increased in recent years. However, the current structure for interaction among the pharmaceutical sponsor funding a drug or device development program,...
10.
Harrigan E, Miceli J, Anziano R, Watsky E, Reeves K, Cutler N, et al.
J Clin Psychopharmacol . 2004 Jan; 24(1):62-9. PMID: 14709949
Many drugs have been associated with QTc prolongation and, in some cases, this is augmented by concomitant administration with metabolic inhibitors. The effects of 6 antipsychotics on the QTc interval...