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Neal Cody

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Articles 9
Citations 86
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Recent Articles
1.
Rigobello R, Shaw J, Ilg D, Zimmerman R, Edelmann L, Kornreich R, et al.
Clin Pharmacol Ther . 2023 Jun; 114(2):262-265. PMID: 37314952
Aminoglycoside antibiotic exposure can result in ototoxicity and irreversible hearing loss among individuals that harbor the m.1555A>G variant in the mitochondrial 12S rRNA gene, MT-RNR1. Importantly, pre-emptive m.1555A>G screening has...
2.
Scott E, Yang Y, Botton M, Seki Y, Hoshitsuki K, Harting J, et al.
Hum Mutat . 2022 Sep; 43(11):1557-1566. PMID: 36057977
To determine the phase of NUDT15 sequence variants for more comprehensive star (*) allele diplotyping, we developed a novel long-read single-molecule real-time HiFi amplicon sequencing method. A 10.5 kb NUDT15...
3.
Pratt V, Wang W, Boone E, Broeckel U, Cody N, Edelmann L, et al.
J Mol Diagn . 2022 Aug; 24(10):1079-1088. PMID: 35931342
Pharmacogenetic testing is increasingly provided by clinical and research laboratories; however, only a limited number of quality control and reference materials are currently available for many of the TPMT and...
4.
Markmiller S, Sathe S, Server K, Nguyen T, Fulzele A, Cody N, et al.
Cell Rep . 2021 Sep; 36(10):109685. PMID: 34496257
Persistent cytoplasmic aggregates containing RNA binding proteins (RBPs) are central to the pathogenesis of late-onset neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS). These aggregates share components, molecular mechanisms, and...
5.
Mcdermott J, Wolf J, Hoshitsuki K, Huddart R, Caudle K, Whirl-Carrillo M, et al.
Clin Pharmacol Ther . 2021 May; 111(2):366-372. PMID: 34032273
Aminoglycosides are widely used antibiotics with notable side effects, such as nephrotoxicity, vestibulotoxicity, and sensorineural hearing loss (cochleotoxicity). MT-RNR1 is a gene that encodes the 12s rRNA subunit and is...
6.
Scott S, Scott E, Seki Y, Chen A, Wallsten R, Obeng A, et al.
Clin Transl Sci . 2020 Sep; 14(1):204-213. PMID: 32931151
To develop a novel pharmacogenetic genotyping panel, a multidisciplinary team evaluated available evidence and selected 29 genes implicated in interindividual drug response variability, including 130 sequence variants and additional copy...
7.
Rigobello R, Rahawi S, Wallsten R, Cody N, Nicoletti P, Obeng A, et al.
Clin Pharmacol Ther . 2020 Jun; 108(5):924-928. PMID: 32592592
No abstract available.
8.
Loskove Y, Yasuda M, Chen B, Nazarenko I, Cody N, Desnick R
Mol Genet Metab . 2018 Nov; 128(3):352-357. PMID: 30385147
The acute hepatic porphyrias (AHPs) are inborn errors of heme biosynthesis, which include three autosomal dominant porphyrias, Acute Intermittent Porphyria (AIP), Hereditary Coproporphyria (HCP), and Variegate Porphyria (VP), and the...
9.
Legendre F, Cody N, Iampietro C, Bergalet J, Lefebvre F, Moquin-Beaudry G, et al.
J Vis Exp . 2013 Feb; (71):e50057. PMID: 23407302
Assessing the expression pattern of a gene, as well as the subcellular localization properties of its transcribed RNA, are key features for understanding its biological function during development. RNA in...