Nduka Amankulor
Overview
Explore the profile of Nduka Amankulor including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
786
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0
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Recent Articles
1.
Akbari H, Bakas S, Sako C, Kazerooni A, Villanueva-Meyer J, Garcia J, et al.
Neuro Oncol
. 2024 Dec;
PMID: 39665363
Background: Glioblastoma is the most aggressive adult primary brain cancer, characterized by significant heterogeneity, posing challenges for patient management, treatment planning, and clinical trial stratification. Methods: We developed a highly...
2.
Casillo S, Gatesman T, Chilukuri A, Varadharajan S, Johnson B, David Premkumar D, et al.
Cell Rep
. 2023 Dec;
43(1):113557.
PMID: 38113141
Metabolic reprogramming in pediatric diffuse midline glioma is driven by gene expression changes induced by the hallmark histone mutation H3K27M, which results in aberrantly permissive activation of oncogenic signaling pathways....
3.
Singh S, Wang Y, Habib A, Priyadarshini M, Kodavali C, Chen A, et al.
Front Oncol
. 2023 Oct;
13:1279806.
PMID: 37881491
Glioblastoma (GBM) is fatal and the study of therapeutic resistance, disease progression, and drug discovery in GBM or glioma stem cells is often hindered by limited resources. This limitation slows...
4.
Youngblood M, Erson-Omay Z, Li C, Najem H, Coskun S, Tyrtova E, et al.
Nat Commun
. 2023 Oct;
14(1):6279.
PMID: 37805627
Hedgehog signaling mediates embryologic development of the central nervous system and other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular proliferation. Meningiomas, the most common primary brain...
5.
Xu E, Stone S, Zhong Y, Golenberg N, Qiu L, Abdullaev Z, et al.
J Neuropathol Exp Neurol
. 2023 Sep;
82(11):966-969.
PMID: 37742132
No abstract available.
6.
Sussman J, Xu J, Amankulor N, Tan K
Neurooncol Adv
. 2023 Sep;
5(1):vdad101.
PMID: 37706202
Malignant gliomas are incurable brain neoplasms with dismal prognoses and near-universal fatality, with minimal therapeutic progress despite billions of dollars invested in research and clinical trials over the last 2...
7.
Zhang D, Li A, Hu G, Huang M, Yang F, Zhang L, et al.
Cell Metab
. 2023 Feb;
35(3):517-534.e8.
PMID: 36804058
The efficacy of immunotherapy is limited by the paucity of T cells delivered and infiltrated into the tumors through aberrant tumor vasculature. Here, we report that phosphoglycerate dehydrogenase (PHGDH)-mediated endothelial...
8.
Agarwal P, Beale O, Zhang X, Sandlesh P, Jaman E, Amankulor N
World Neurosurg
. 2022 Apr;
163:e349-e362.
PMID: 35390499
Objective: Immunotherapy has revolutionized cancer treatment in the past decade, but significant hurdles remain. Human studies with immune checkpoint inhibitors targeting programmed cell death protein have demonstrated suboptimal efficacy in...
9.
Beiriger J, Habib A, Jovanovich N, Kodavali C, Edwards L, Amankulor N, et al.
Front Oncol
. 2022 Apr;
12:790976.
PMID: 35359410
Glioblastoma (GBM) is a malignant tumor with a median survival rate of 15-16 months with standard care; however, cases of successful treatment offer hope that an enhanced understanding of the...
10.
Marker D, Agnihotri S, Amankulor N, Murdoch G, Pearce T
Neurooncol Adv
. 2022 Jan;
4(1):vdab182.
PMID: 35047821
Background: Infiltrative astrocytic tumors with and without isocitrate dehydrogenase (IDH) mutation frequently contain mutations in the tumor suppressor gene. Disruption of normal p53 protein activity confers neoplastic cells with a...