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» Authors » Ndona N Nsumu

Ndona N Nsumu

Explore the profile of Ndona N Nsumu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 100
Followers 0
Related Specialties
Genetics
Hematology
Neurology
Top 10 Co-Authors
Robert A White
Steven G McNulty
Brandon P Brewer
Daniel P Heruth
Leigh A Boydston
Koji Shimizu
Barbara Fegley
Derek P Logsdon
Krista Blackmore
Inna V Sokolovsky
Published In
Genomics
Blood
Blood Cells Mol Dis
Cell Death Discov
Neuromuscul Disord
Affiliations
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Recent Articles
1.
Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis
Li X, Islam S, Xiong M, Nsumu N, Lee Jr M, Zhang L, et al.
Cell Death Discov . 2019 Feb; 5:62. PMID: 30774990
Nicotinamide phosphoribosyltransferase (NAMPT) functions in NAD synthesis, apoptosis, and inflammation. Dysregulation of NAMPT has been associated with several inflammatory diseases, including rheumatoid arthritis (RA). The purpose of this study was...
2.
Mutation in erythroid specific transcription factor KLF1 causes Hereditary Spherocytosis in the Nan hemolytic anemia mouse model
Heruth D, Hawkins T, Logsdon D, Gibson M, Sokolovsky I, Nsumu N, et al.
Genomics . 2010 Aug; 96(5):303-7. PMID: 20691777
KLF1 regulates definitive erythropoiesis of red blood cells by facilitating transcription through high affinity binding to CACCC elements within its erythroid specific target genes including those encoding erythrocyte membrane skeleton...
3.
Hematologic characterization and chromosomal localization of the novel dominantly inherited mouse hemolytic anemia, neonatal anemia (Nan)
White R, Sokolovsky I, Britt M, Nsumu N, Logsdon D, McNulty S, et al.
Blood Cells Mol Dis . 2009 May; 43(2):141-8. PMID: 19409822
One of the most commonly inherited anemias in man is Hereditary Spherocytosis (HS) with an incidence of 1 in 2000 for persons of Northern European descent. Mouse models of HS...
4.
Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene
Gaedigk R, Law D, Fitzgerald-Gustafson K, McNulty S, Nsumu N, Modrcin A, et al.
Neuromuscul Disord . 2006 Feb; 16(3):192-203. PMID: 16487708
Duchenne muscular dystrophy is a progressive muscle disease characterized by increasing muscle weakness and death by the third decade. mdx mice exhibit the underlying muscle disease but appear physically normal...
5.
Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking
White R, Boydston L, Brookshier T, McNulty S, Nsumu N, Brewer B, et al.
Genomics . 2005 Nov; 86(6):668-73. PMID: 16289749
Defects in iron absorption and utilization lead to iron deficiency and anemia. While iron transport by transferrin receptor-mediated endocytosis is well understood, it is not completely clear how iron is...
6.
Positional cloning of the Ttc7 gene required for normal iron homeostasis and mutated in hea and fsn anemia mice
White R, McNulty S, Nsumu N, Boydston L, Brewer B, Shimizu K
Genomics . 2005 Feb; 85(3):330-7. PMID: 15718100
Genes playing essential roles in iron homeostasis have yet to be identified. We report the discovery of a strong candidate gene affecting iron homeostasis in two allelic anemia mouse mutants:...
7.
Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse
White R, McNulty S, Roman S, Garg U, Wirtz E, Kohlbrecher D, et al.
Blood . 2004 May; 104(5):1511-8. PMID: 15155459
Understanding iron metabolism has been enhanced by identification of genes for iron deficiency mouse mutants. We characterized the genetics and iron metabolism of the severe anemia mutant hea (hereditary erythroblastic...