Nchafatso G Obonyo
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Explore the profile of Nchafatso G Obonyo including associated specialties, affiliations and a list of published articles.
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34
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228
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Recent Articles
1.
Obonyo N, Sela D, White N, Tunbridge M, Sim B, Rachakonda R, et al.
Vox Sang
. 2025 Mar;
PMID: 40031908
Background And Objectives: Randomized controlled trials have demonstrated morbidity and mortality in critically ill patients are unaffected by transfusing fresh (<7 days old) packed red blood cells (pRBCs); however, there...
2.
Karnik V, Colombo S, Rickards L, Heinsar S, Hoe L, Wildi K, et al.
Intensive Care Med Exp
. 2024 Nov;
12(1):109.
PMID: 39602032
Open-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potential strategy to mitigate postoperative acute respiratory distress syndrome (ARDS). We utilized an ovine HTx model...
3.
Obonyo N, Raman S, Suen J, Peters K, Phan M, Passmore M, et al.
Intensive Care Med Exp
. 2024 Oct;
12(1):94.
PMID: 39467921
Background: Escherichia coli is the most common cause of human bloodstream infections and bacterial sepsis/septic shock. However, translation of preclinical septic shock resuscitative therapies remains limited mainly due to low-fidelity...
4.
Obonyo N, Dhanapathy V, White N, Sela D, Rachakonda R, Tunbridge M, et al.
J Cardiothorac Surg
. 2024 Aug;
19(1):475.
PMID: 39090687
Background: Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of transfusing...
5.
Nonaka H, Ratsep I, Obonyo N, Suen J, Fraser J, Chan J
Front Cardiovasc Med
. 2024 Jul;
11:1365798.
PMID: 39011493
Right ventricle (RV) failure is a common complication of many cardiopulmonary diseases. Since it has a significant adverse impact on prognosis, precise determination of RV function is crucial to guide...
6.
Sato K, Heinsar S, Chan J, Farah S, Wildi K, Obonyo N, et al.
Eur J Clin Invest
. 2024 Jun;
54(10):e14263.
PMID: 38849326
Background: Left ventricular stroke work index (LVSWI) and cardiac power index (CPI) account for the haemodynamic load of the left ventricle and are promising prognostic values in cardiogenic shock. However,...
7.
Sato K, Hoe L, Chan J, Obonyo N, Wildi K, Heinsar S, et al.
Eur J Clin Invest
. 2024 Jun;
54(10):e14259.
PMID: 38845111
Background: The commonest echocardiographic measurement, left ventricular ejection fraction, can not necessarily predict mortality of recipients following heart transplantation potentially due to afterload dependency. Afterload-independent left ventricular stroke work index...
8.
Kariuki N, Kimani E, Jowi C, Wamalwa D, Suen J, Fraser J, et al.
BMC Cardiovasc Disord
. 2024 May;
24(1):260.
PMID: 38769516
Introduction: Use of doxorubicin, an anthracycline chemotherapeutic agent has been associated with late-occurring cardiac toxicities. Detection of early-occurring cardiac effects of cancer chemotherapy is essential to prevent occurrence of adverse...
9.
Kirengo T, Dossajee H, Onyango E, Rachakonda R, Schneider B, Sela D, et al.
Syst Rev
. 2024 Mar;
13(1):89.
PMID: 38500200
Introduction: In December 2019, the COVID-19 pandemic highlighted the urgent need for rapid collaboration, research, and interventions. International research collaborations foster more significant responses to rapid global changes by enabling...
10.
Obonyo N, Sela D, Raman S, Rachakonda R, Schneider B, Hoe L, et al.
Syst Rev
. 2023 Nov;
12(1):221.
PMID: 37990333
Introduction: Shock-induced endotheliopathy (SHINE), defined as a profound sympathoadrenal hyperactivation in shock states leading to endothelial activation, glycocalyx damage, and eventual compromise of end-organ perfusion, was first described in 2017....