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Nazila V Jafari

Explore the profile of Nazila V Jafari including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 137
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Recent Articles
1.
Jafari N, Rohn J
Front Cell Infect Microbiol . 2023 Apr; 13:1128132. PMID: 37051302
Introduction: Murine models of urinary tract infection (UTI) have improved our understanding of host-pathogen interactions. However, given differences between rodent and human bladders which may modulate host and bacterial response,...
2.
Jafari N, Rohn J
Mucosal Immunol . 2022 Sep; 15(6):1127-1142. PMID: 36180582
All mucosal surfaces must deal with the challenge of exposure to the outside world. The urothelium is a highly specialized layer of stratified epithelial cells lining the inner surface of...
3.
Aydogdu M, Rohn J, Jafari N, Brako F, Homer-Vanniasinkam S, Edirisinghe M
Adv Sci (Weinh) . 2022 Jan; 9(11):e2104495. PMID: 35037418
COVID-19 vaccines have constituted a substantial scientific leap in countering severe acute respiratory syndrome type 2-causing coronavirus (SARS-CoV-2), and worldwide implementation of vaccination programs has significantly contributed to the global...
4.
Lau W, Dharmasena D, Horsley H, Jafari N, Malone-Lee J, Eleanor Stride , et al.
J Control Release . 2020 Sep; 328:490-502. PMID: 32882271
A significant proportion of urinary tract infection (UTI) patients experience recurrent episodes, due to deep tissue infection and treatment-resistant bacterial reservoirs. Direct bladder instillation of antibiotics has proved disappointing in...
5.
Hubbard A, Jafari N, Feasey N, Rohn J, Roberts A
Front Microbiol . 2019 Sep; 10:2001. PMID: 31555237
The fitness cost to bacteria of acquisition of resistance determinants is critically under-investigated, and the identification and exploitation of these fitness costs may lead to novel therapeutic strategies that prevent...
6.
Edwards L, Nowocin A, Jafari N, Meader L, Brown K, Sarde A, et al.
Circulation . 2017 Aug; 137(5):488-503. PMID: 28775077
Background: Cardiac transplantation is an excellent treatment for end-stage heart disease. However, rejection of the donor graft, in particular, by chronic rejection leading to cardiac allograft vasculopathy, remains a major...
7.
Jafari N, Kuehne S, Minton N, Allan E, Bajaj-Elliott M
Anaerobe . 2015 Dec; 37:96-102. PMID: 26708704
Clostridium difficile infection is one of the leading causes of healthcare associated diarrhoea in the developed world. Although the contribution of C. difficile toxins to disease pathogenesis is now well...
8.
Jafari N, Songane M, Stabler R, Elawad M, Wren B, Allan E, et al.
Infect Immun . 2014 Sep; 82(12):4989-96. PMID: 25225246
Clostridium difficile is an important nosocomial pathogen and the leading cause of antibiotic-associated diarrhea. Multilocus sequence typing indicates that C. difficile strains belong to five distinct genetic clades encompassing several...
9.
Jafari N, Kuehne S, Bryant C, Elawad M, Wren B, Minton N, et al.
PLoS One . 2013 Aug; 8(7):e69846. PMID: 23922820
Clostridium difficile infection (CDI) is the leading cause of hospital and community-acquired antibiotic-associated diarrhoea and currently represents a significant health burden. Although the role and contribution of C. difficile toxins...
10.
Jafari N, Allan E, Bajaj-Elliott M
Methods Mol Biol . 2010 Jul; 646:135-46. PMID: 20597007
Clostridium difficile is a gram-positive, spore-forming, toxin-producing anaerobic bacillus that is being increasingly implicated as the leading cause of diarrhea and colitis, particularly in hospitalized, elderly patients. Studies to date...