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Nawshaba Nawreen

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Articles 12
Citations 148
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Recent Articles
1.
Nawreen N, Oshima K, Chambers J, Smail M, Herman J
Stress . 2024 Jul; 27(1):2361238. PMID: 38962839
Chronic stress leads to hypofunction of the medial prefrontal cortex (mPFC), mechanisms of which remain to be determined. Enhanced activation of GABAergic of parvalbumin (PV) expressing interneurons (INs) is thought...
2.
Smail M, Smith B, Shukla R, Alganem K, Eby H, Bollinger J, et al.
Mol Psychiatry . 2023 Aug; 28(11):4729-4741. PMID: 37644175
Psychological loss is a common experience that erodes well-being and negatively impacts quality of life. The molecular underpinnings of loss are poorly understood. Here, we investigate the mechanisms of loss...
3.
Cotella E, Nawreen N, Moloney R, Martelle S, Oshima K, Lemen P, et al.
Biol Psychiatry Glob Open Sci . 2023 May; 3(2):274-282. PMID: 37124346
Background: Adolescent brains are sensitive to stressors. However, under certain circumstances, developmental stress can promote an adaptive phenotype, allowing individuals to cope better with adverse situations in adulthood, thereby contributing...
4.
Kraus K, Nawreen N, Godale C, Chordia A, Packard B, LaSarge C, et al.
Neurobiol Dis . 2023 Jan; 178:106014. PMID: 36702319
Status epilepticus (SE) is a life-threatening medical emergency with significant morbidity and mortality. SE is associated with a robust and sustained increase in serum glucocorticoids, reaching concentrations sufficient to activate...
5.
DePasquale E, Alganem K, Bentea E, Nawreen N, McGuire J, Tomar T, et al.
PLoS One . 2021 Dec; 16(12):e0260440. PMID: 34919543
Phosphorylation by serine-threonine and tyrosine kinases is critical for determining protein function. Array-based platforms for measuring reporter peptide signal levels allow for differential phosphorylation analysis between conditions for distinct active...
6.
Nawreen N, Baccei M, Herman J
Front Cell Neurosci . 2021 Aug; 15:705660. PMID: 34366790
Post-traumatic stress disorder (PTSD) is a chronic, debilitating mental illness marked by abnormal fear responses and deficits in extinction of fear memories. The pathophysiology of PTSD is linked to decreased...
7.
Martelle S, Cotella E, Nawreen N, Chen C, Packard B, Fitzgerald M, et al.
Stress . 2021 Mar; 24(2):196-205. PMID: 33726625
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an excitatory neuromodulatory peptide strongly implicated in nervous stress processing. Human polymorphism of the primary PACAP receptor (PAC1) is linked to psychiatric disorders, including...
8.
Herman J, Nawreen N, Smail M, Cotella E
Stress . 2020 Dec; 23(6):617-632. PMID: 33345670
Regulation of stress reactivity is a fundamental priority of all organisms. Stress responses are critical for survival, yet can also cause physical and psychological damage. This review provides a synopsis...
9.
Nawreen N, Cotella E, Morano R, Mahbod P, Dalal K, Fitzgerald M, et al.
eNeuro . 2020 Oct; 7(5). PMID: 33055196
Hypofunction of the prefrontal cortex (PFC) contributes to stress-related neuropsychiatric illnesses. Mechanisms leading to prefrontal hypoactivity remain to be determined. Prior evidence suggests that chronic stress leads to an increase...
10.
Smail M, Smith B, Nawreen N, Herman J
Pharmacol Biochem Behav . 2020 Jul; 197:172993. PMID: 32659243
Stress exposure can produce profound changes in physiology and behavior that can impair health and well-being. Of note, stress exposure is linked to anxiety disorders and depression in humans. The...