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Navein Arumugasaamy

Explore the profile of Navein Arumugasaamy including associated specialties, affiliations and a list of published articles. Areas
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Citations 340
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Recent Articles
1.
Arumugasaamy N, Rock K, Kuo C, Bale T, Fisher J
Adv Drug Deliv Rev . 2020 Aug; 161-162:161-175. PMID: 32858104
Methods to evaluate maternal-fetal transport across the placental barrier have generally involved clinical observations after-the-fact, ex vivo perfused placenta studies, or in vitro Transwell assays. Given the ethical and technical...
2.
Hurley-Novatny A, Arumugasaamy N, Kimicata M, Baker H, Mikos A, Fisher J
Biomed Mater . 2020 Jun; 15(5):055035. PMID: 32526725
Severe tendon and ligament injuries are estimated to affect between 300 000 and 400 000 people annually. Surgical repairs of these injuries often have poor long-term clinical outcomes because of...
3.
Arumugasaamy N, Hurley-Novatny A, Lembong J, Kim P, Fisher J
Acta Biomater . 2019 Sep; 99:258-268. PMID: 31536839
Selective serotonin reuptake inhibitors (SSRIs) have been shown to hinder cardiomyocyte signaling, raising concerns about their safety during pregnancy. Approaches to assess SSRI-induced effects on fetal cardiovascular cells following passage...
4.
Arumugasaamy N, Gudelsky A, Hurley-Novatny A, Kim P, Fisher J
Adv Healthc Mater . 2019 Aug; 8(18):e1900476. PMID: 31407872
Medications taken during pregnancy may significantly impact fetal development, yet there are few studies that rigorously assess medication safety due to ethical concerns. Selective serotonin reuptake inhibitors (SSRIs) are a...
5.
Lerman M, Muramoto S, Arumugasaamy N, Van Order M, Lembong J, Gerald A, et al.
J Biomed Mater Res B Appl Biomater . 2019 Mar; 107(8):2566-2578. PMID: 30821930
There is a growing interest in 3D printing to fabricate culture substrates; however, the surface properties of the scaffold remain pertinent to elicit targeted and expected cell responses. Traditional 2D...
6.
Arumugasaamy N, Navarro J, Leach J, Kim P, Fisher J
Ann Biomed Eng . 2018 Sep; 47(1):1-21. PMID: 30218224
Epithelial barriers are the body's natural defense system to regulating passage from one domain to another. In our efforts to understand what can and cannot cross these barriers, models have...
7.
Arumugasaamy N, Ettehadieh L, Kuo C, Paquin-Proulx D, Kitchen S, Santoro M, et al.
Ann Biomed Eng . 2018 Jul; 46(12):1963-1974. PMID: 30003503
Recent global epidemics of viral infection such as Zika virus (ZIKV) and associated birth defects from maternal-fetal viral transmission highlights the critical unmet need for experimental models that adequately recapitulates...
8.
Kuo C, Guo T, Cabrera-Luque J, Arumugasaamy N, Bracaglia L, Garcia-Vivas A, et al.
J Biomed Mater Res A . 2018 Jan; 106(6):1476-1487. PMID: 29368378
Fetal cytotrophoblast invasion of maternal decidual vasculature is necessary to normal pregnancy. In preeclampsia, there is shallow invasion and abnormal remodeling of the uterine vasculature that lead to significant maternal...
9.
Bracaglia L, Smith B, Watson E, Arumugasaamy N, Mikos A, Fisher J
Acta Biomater . 2017 Mar; 56:3-13. PMID: 28342878
Statement Of Significance: Additive manufacturing techniques have given tissue engineers the ability to precisely recapitulate the native architecture present within tissue. In addition, these techniques can be leveraged to create...
10.
Lamichhane T, Jeyaram A, Patel D, Parajuli B, Livingston N, Arumugasaamy N, et al.
Cell Mol Bioeng . 2016 Nov; 9(3):315-324. PMID: 27800035
Extracellular vesicles (EVs), including exosomes and microvesicles, have emerged as promising drug delivery vehicles for small RNAs (siRNA and miRNA) due to their natural role in intercellular RNA transport. However,...