Naveed Shams
Overview
Explore the profile of Naveed Shams including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
970
Followers
0
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Recent Articles
1.
Gonzalez V, Berger B, Goldberg R, Gordon C, Khurana R, Angeles R, et al.
Transl Vis Sci Technol
. 2021 Dec;
10(14):27.
PMID: 34935908
Purpose: Carotuximab (DE-122) is a novel endoglin antibody that exhibits potent anti-angiogenic activity. The aim of this study was to evaluate the safety and tolerability of a single intravitreal injection...
2.
Aihara M, Ropo A, Lu F, Kawata H, Iwata A, Odani-Kawabata N, et al.
Jpn J Ophthalmol
. 2020 Jun;
64(4):398-406.
PMID: 32572719
Purpose: Omidenepag isopropyl (OMDI) is the prodrug of omidenepag, a selective, non-prostaglandin, prostanoid EP2 receptor agonist, which has been shown to lower intraocular pressure (IOP) in patients with glaucoma and...
3.
Merrill P, Clark W, Banker A, Fardeau C, Franco P, LeHoang P, et al.
Ophthalmology
. 2020 Jun;
127(10):1405-1415.
PMID: 32564920
Purpose: To evaluate the efficacy and safety of intravitreal sirolimus in the management of noninfectious uveitis of the posterior segment (NIU-PS). Design: Combined analysis of 2 phase 3, randomized, double-masked,...
4.
Iwamura R, Tanaka M, Okanari E, Kirihara T, Odani-Kawabata N, Shams N, et al.
J Med Chem
. 2018 Jul;
61(15):6869-6891.
PMID: 29995405
EP2 receptor agonists are expected to be effective ocular hypotensive agents; however, it has been suggested that agonism to other EP receptor subtypes may lead to undesirable effects. Through medicinal...
5.
Kirihara T, Taniguchi T, Yamamura K, Iwamura R, Yoneda K, Odani-Kawabata N, et al.
Invest Ophthalmol Vis Sci
. 2018 Jan;
59(1):145-153.
PMID: 29332128
Purpose: The objective of this study was to investigate the pharmacologic characteristics of omidenepag isopropyl (OMDI), a compound developed as a novel intraocular pressure (IOP)-lowering agent, with better IOP control...
6.
Nguyen Q, Merrill P, Clark W, Banker A, Fardeau C, Franco P, et al.
Ophthalmology
. 2016 Oct;
123(11):2413-2423.
PMID: 27692526
Purpose: To evaluate the efficacy and safety of intravitreal sirolimus in the treatment of noninfectious uveitis (NIU) of the posterior segment (i.e., posterior, intermediate, or panuveitis). Design: Phase III, randomized,...
7.
Nguyen Q, Ibrahim M, Watters A, Bittencourt M, Yohannan J, Sepah Y, et al.
J Ophthalmic Inflamm Infect
. 2013 Mar;
3(1):32.
PMID: 23514595
Background: The purpose of this study is to evaluate the ocular tolerability and efficacy of sirolimus administered as subconjunctival or intravitreal injections in patients with non-infectious uveitis. Sirolimus as a...
8.
Regillo C, Brown D, Abraham P, Yue H, Ianchulev T, Schneider S, et al.
Am J Ophthalmol
. 2008 Jan;
145(2):239-248.
PMID: 18222192
Purpose: To evaluate the efficacy and safety of ranibizumab administered monthly for three months and then quarterly in patients with subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD)....
9.
Ferrara N, Damico L, Shams N, Lowman H, Kim R
Retina
. 2006 Oct;
26(8):859-70.
PMID: 17031284
Background: Angiogenesis is a key aspect of the wet form of age-related neovascular (AMD), the leading cause of blindness in the elderly population. Substantial evidence indicated that vascular endothelial growth...
10.
Shams N, Ianchulev T
Ophthalmol Clin North Am
. 2006 Aug;
19(3):335-44.
PMID: 16935208
VEGF-A is a critical regulator of ocular angiogenesis and vascular permeability and is involved in the pathogenesis of several ocular diseases involving neovascularization or increased vascular permeability, such as neovascular...