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Nathane S Felix

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Articles 9
Citations 118
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Recent Articles
1.
Felix N, Maia L, Rocha N, Rodrigues G, Medeiros M, da Silva L, et al.
Front Physiol . 2022 Nov; 13:992401. PMID: 36388107
Fluid regimens in acute respiratory distress syndrome (ARDS) are conflicting. The amount of fluid and positive end-expiratory pressure (PEEP) level may interact leading to ventilator-induced lung injury (VILI). We therefore...
2.
Rocco P, Silva P, Cruz F, Tierno P, Rabello E, Junior J, et al.
Front Med (Lausanne) . 2022 May; 9:844728. PMID: 35492335
Background: Nitazoxanide exerts antiviral activity and and anti-inflammatory effects, but its impact on patients hospitalized with COVID-19 pneumonia is uncertain. Methods: A multicentre, randomized, double-blind, placebo-controlled trial was conducted in...
3.
Fernandes M, Rocha N, Felix N, Rodrigues G, Silva L, Coelho M, et al.
J Appl Physiol (1985) . 2021 Dec; 132(2):375-387. PMID: 34941443
Increases in positive end-expiratory pressure (PEEP) or recruitment maneuvers may increase stress in lung parenchyma, extracellular matrix, and lung vessels; however, adaptative responses may occur. We evaluated the effects of...
4.
Felix N, Samary C, Cruz F, Rocha N, Fernandes M, Machado J, et al.
Anesthesiology . 2019 Mar; 130(5):767-777. PMID: 30870161
Background: This study hypothesized that, in experimental mild acute respiratory distress syndrome, lung damage caused by high tidal volume (VT) could be attenuated if VT increased slowly enough to progressively...
5.
De Mendonca L, Felix N, Blanco N, da Silva J, Ferreira T, Abreu S, et al.
Stem Cell Res Ther . 2017 Oct; 8(1):220. PMID: 28974252
Background: Experimental research has reported beneficial effects of mesenchymal stromal cell (MSC) therapy in pulmonary arterial hypertension (PAH). However, these studies either were based on prophylactic protocols or assessed basic...
6.
Santos C, Santos R, Moraes L, Samary C, Felix N, Silva J, et al.
PLoS One . 2017 May; 12(5):e0178207. PMID: 28542443
Intra-abdominal hypertension (IAH) may co-occur with the acute respiratory distress syndrome (ARDS), with significant impact on morbidity and mortality. Lung-protective controlled mechanical ventilation with low tidal volume and positive end-expiratory...
7.
Araujo M, Santos C, Samary C, Heil L, Cavalcanti V, Cruz F, et al.
Anesth Analg . 2017 Mar; 125(2):491-498. PMID: 28277329
Background: Volatile anesthetics modulate inflammation in acute respiratory distress syndrome (ARDS). However, it is unclear whether they act differently depending on ARDS etiology. We hypothesized that the in vivo and...
8.
Samary C, Moraes L, Santos C, Huhle R, Santos R, Ornellas D, et al.
Crit Care Med . 2016 Mar; 44(7):e553-62. PMID: 26963321
Objectives: The biologic effects of variable ventilation may depend on the etiology of acute respiratory distress syndrome. We compared variable and conventional ventilation in experimental pulmonary and extrapulmonary acute respiratory...
9.
Samary C, Santos R, Santos C, Felix N, Bentes M, Barboza T, et al.
Anesthesiology . 2015 Jun; 123(2):423-33. PMID: 26039328
Background: Ventilator-induced lung injury has been attributed to the interaction of several factors: tidal volume (VT), positive end-expiratory pressure (PEEP), transpulmonary driving pressure (difference between transpulmonary pressure at end-inspiration and...