Nathan J Alves
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Explore the profile of Nathan J Alves including associated specialties, affiliations and a list of published articles.
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42
Citations
481
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Recent Articles
1.
Christodoulides A, Hall A, Umesh A, Alves N
J Vis Exp
. 2024 May;
(206).
PMID: 38709048
Thromboembolism and related complications are a leading cause of morbidity and mortality worldwide and various assays have been developed to test thrombolytic drug efficiency both in vitro and in vivo....
2.
Christodoulides A, Hall A, Alves N
Front Public Health
. 2023 Jul;
11:1215817.
PMID: 37521965
This study investigates the influence of microplastics on blood clotting. It addresses the lack of comprehensive research on the effects of microplastic size and surface modification on clotting dynamics in...
3.
Zeng Z, Christodoulides A, Alves N
Bioeng Transl Med
. 2023 May;
8(3):e10511.
PMID: 37206217
A great need exists for the development of a more representative in-vitro model to efficiently screen novel thrombolytic therapies. We herein report the design, validation, and characterization of a highly...
4.
Zeng Z, Nallan Chakravarthula T, Christodoulides A, Hall A, Alves N
J Mater Sci Mater Med
. 2023 May;
34(5):24.
PMID: 37173603
Thrombosis can lead to a wide variety of life-threatening circumstances. As current thrombolytic drug screening models often poorly predict drug profiles, leading to failure of thrombolytic therapy or clinical translation,...
5.
Tran D, Stelflug N, Hall A, Nallan Chakravarthula T, Alves N
Biomolecules
. 2022 Dec;
12(12).
PMID: 36551292
Micro/nanoplastics, whether manufactured or resulting from environmental degradation, can enter the body through ingestion, inhalation, or dermal pathways. Previous research has found that nanoplastics with diameters of ≤100 nm can...
6.
Nallan Chakravarthula T, Zeng Z, Alves N
ChemMedChem
. 2022 Sep;
17(22):e202200364.
PMID: 36111842
There is an emerging interest in utilizing synthetic multivalent inhibitors that comprise of multiple inhibitor moieties linked on a common scaffold to achieve strong and selective enzyme inhibition. As multivalent...
7.
Crowder J, Zeng Z, Novak A, Alves N, Linnemann A
Islets
. 2022 Mar;
14(1):128-138.
PMID: 35331085
Metabolic dysfunction of β-cells has been implicated as a contributor to diabetes pathogenesis, and efforts are ongoing to optimize analytical techniques that evaluate islet metabolism. High-resolution respirometry offers sensitive measurements...
8.
Whitehead A, Alves N
PLoS One
. 2022 Feb;
17(2):e0263848.
PMID: 35143578
Objectives: There has long existed significant underrepresentation of minority students in STEM training and careers. Ongoing efforts to improve opportunities and participation for underrepresented minority students have focused on multiple...
9.
Zagorski J, Neto-Neves E, Alves N, Fisher A, Kline J
Physiol Rep
. 2022 Jan;
10(1):e15156.
PMID: 35001565
Acute pulmonary embolism (PE) does not always resolve after treatment and can progress to chronic thromboembolic disease (CTED) or the more severe chronic thromboembolic pulmonary hypertension (CTEPH). The mechanisms surrounding...
10.
Zeng Z, Nallan Chakravarthula T, Muralidharan C, Hall A, Linnemann A, Alves N
J Mater Chem B
. 2021 Oct;
9(45):9295-9307.
PMID: 34698753
Impaired fibrinolysis has long been considered as a risk factor for venous thromboembolism. Fibrin clots formed at physiological concentrations are promising substrates for monitoring fibrinolytic performance as they offer clot...