Nathan C Peters
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Explore the profile of Nathan C Peters including associated specialties, affiliations and a list of published articles.
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32
Citations
1329
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Recent Articles
1.
Gonzales G, Huang S, Wilkinson L, Nguyen J, Sikdar S, Piot C, et al.
Sci Immunol
. 2024 Nov;
9(101):eadn2168.
PMID: 39485861
Conventional dendritic cells (cDCs) generate protective cytotoxic T lymphocyte (CTL) responses against extracellular pathogens and tumors. This is achieved through a process known as cross-presentation (XP), and, despite its biological...
2.
Nzelu C, Meneses C, Bowhay C, Coutinho-Abreu I, Bennett E, Bahrami S, et al.
Parasit Vectors
. 2024 Jan;
17(1):11.
PMID: 38183132
Background: Vector sand fly colonies are a critical component of studies aimed at improving the understanding of the neglected tropical disease leishmaniasis and alleviating its global impact. However, among laboratory-colonized...
3.
Ranson A, Carneiro M, Perks B, Penner R, Melo L, Canton J, et al.
J Immunol
. 2023 May;
211(1):103-117.
PMID: 37195185
Recruited neutrophils are among the first phagocytic cells to interact with the phagosomal pathogen Leishmania following inoculation into the mammalian dermis. Analysis of Leishmania-infected neutrophils has revealed alterations in neutrophil...
4.
Peters N, Khan N, Mody C
Trends Immunol
. 2022 Dec;
44(1):22-31.
PMID: 36494273
Prophylactic vaccination strategies designed to prevent diseases caused by pathogens using the phagolysosome of innate immune cells as a site of intracellular replication and survival have been largely ineffective. These...
5.
Carneiro M, Peters N
Front Immunol
. 2021 Sep;
12:728848.
PMID: 34557194
Intracellular phagosomal pathogens represent a formidable challenge for innate immune cells, as, paradoxically, these phagocytic cells can act as both host cells that support pathogen replication and, when properly activated,...
6.
Hohman L, Mou Z, Carneiro M, Ferland G, Kratofil R, Kubes P, et al.
PLoS Pathog
. 2021 Sep;
17(9):e1009944.
PMID: 34543348
Intracellular infection with the parasite Leishmania major features a state of concomitant immunity in which CD4+ T helper 1 (Th1) cell-mediated immunity against reinfection coincides with a chronic but sub-clinical...
7.
Chaves M, Lee S, Kamenyeva O, Ghosh K, Peters N, Sacks D
PLoS Pathog
. 2020 Nov;
16(11):e1008674.
PMID: 33137149
There is substantial experimental evidence to indicate that Leishmania infections that are transmitted naturally by the bites of infected sand flies differ in fundamental ways from those initiated by needle...
8.
Batista Carneiro M, Eustaquio Lopes M, Hohman L, Romano A, David B, Kratofil R, et al.
Cell Host Microbe
. 2020 Apr;
27(5):752-768.e7.
PMID: 32298657
The impact of T helper (Th) 1 versus Th2 immunity on intracellular infections is attributed to classical versus alternative activation of macrophages leading to resistance or susceptibility. However, observations in...
9.
Nzelu C, Kato H, Peters N
PLoS Negl Trop Dis
. 2019 Nov;
13(11):e0007698.
PMID: 31697673
Leishmaniasis, caused by protozoan parasites of the Leishmania genus, represents an important health problem in many regions of the world. Lack of effective point-of-care (POC) diagnostic tests applicable in resources-limited...
10.
Hohman L, Peters N
Trends Parasitol
. 2019 May;
35(6):423-435.
PMID: 31080088
The generation of an efficacious vaccine that elicits protective CD4 T cell-mediated immunity has been elusive. The lack of a vaccine against the Leishmania parasite is particularly perplexing as infected...