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Nathan Buchweitz

Explore the profile of Nathan Buchweitz including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Buchweitz N, Sun Y, Cisewski Porto S, Wang S, Reitman C, Yao H, et al.
J Biomech . 2025 Feb; 181:112554. PMID: 39892283
This study provides quantification of fixed charge density in human cervical intervertebral discs. Fixed charge density, which occurs due to negatively charged proteoglycans in the extracellular matrix, is a key...
2.
Kelley J, Buchweitz N, Madden A, Fan H, Hepfer G, Kern M, et al.
JOR Spine . 2024 Nov; 7(4):e70015. PMID: 39544353
Background: Cigarette smoking is a recognized risk factor for orthopedic disorders, particularly intervertebral disc (IVD) degenerative disease. However, the IVD pathophysiology, especially the spatial-temporal remodeling progression in the context of...
3.
Sun S, Xu P, Buchweitz N, Hill C, Ahmadi F, Wilson M, et al.
JCI Insight . 2024 Jul; 9(16). PMID: 38990647
Clarifying multifactorial musculoskeletal disorder etiologies supports risk analysis, development of targeted prevention, and treatment modalities. Deep learning enables comprehensive risk factor identification through systematic analyses of disease data sets but...
4.
Buchweitz N, Sun Y, Cisewski Porto S, Kelley J, Niu Y, Wang S, et al.
J Biomech . 2024 May; 169:112131. PMID: 38739987
Cartilage endplates (CEPs) act as protective mechanical barriers for intervertebral discs (IVDs), yet their heterogeneous structure-function relationships are poorly understood. This study addressed this gap by characterizing and correlating the...
5.
Ren P, Chen P, Reeves R, Buchweitz N, Niu H, Gong H, et al.
J Biomech Eng . 2023 Feb; 145(7). PMID: 36752723
The cartilage endplates (CEPs) on the superior and inferior surfaces of the intervertebral disk (IVD), are the primary nutrient transport pathways between the disk and the vertebral body. Passive diffusion...
6.
Kang I, Baliga U, Chatterjee S, Chakraborty P, Choi S, Buchweitz N, et al.
iScience . 2022 Aug; 25(9):104818. PMID: 36034228
Osteogenesis imperfecta (OI) is characterized by repeated bone fractures. Recent studies have shown that T lymphocytes and regulatory T cells (Tregs) regulate the functions of osteoclasts and osteoblasts, thus playing...