Nathalie Charland
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Explore the profile of Nathalie Charland including associated specialties, affiliations and a list of published articles.
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20
Citations
560
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Recent Articles
1.
Grigoryan L, Feng Y, Bellusci L, Lai L, Wali B, Ellis M, et al.
Sci Immunol
. 2024 Apr;
9(94):eadi8039.
PMID: 38579013
Vaccine adjuvants increase the breadth of serum antibody responses, but whether this is due to the generation of antigen-specific B cell clones with distinct specificities or the maturation of memory...
2.
Kaplonek P, Cizmeci D, Shih-Lu Lee J, Shin S, Fischinger S, Gobeil P, et al.
NPJ Vaccines
. 2023 Feb;
8(1):13.
PMID: 36781879
Despite the success of existing COVID-19 vaccine platforms, the persistent limitations in global deployment of vaccines and waning immunity exhibited by many of the currently deployed vaccine platforms have led...
3.
Gobeil P, Pillet S, Boulay I, Charland N, Lorin A, Cheng M, et al.
Nat Commun
. 2022 Nov;
13(1):6905.
PMID: 36371408
As the SARS-CoV-2 pandemic evolves, vaccine evaluation needs to include consideration of both durability and cross-reactivity. This report expands on previously reported results from a Phase 1 trial of an...
4.
Charland N, Gobeil P, Pillet S, Boulay I, Seguin A, Makarkov A, et al.
NPJ Vaccines
. 2022 Nov;
7(1):142.
PMID: 36351931
The rapid spread of SARS-CoV-2 continues to impact humanity on a global scale with rising total morbidity and mortality. Despite the development of several effective vaccines, new products are needed...
5.
Alvarez F, Istomine R, Hendin H, Hodgins B, Pillet S, Fritz J, et al.
Immunohorizons
. 2022 Jun;
6(6):384-397.
PMID: 35750356
Inactivated influenza vaccines have struggled to provide consistent protection in older individuals. Circumventing immune senescence, an aging of the immune response characterized by weak humoral responses to vaccines, and unchecked...
6.
Hager K, Marc G, Gobeil P, Diaz R, Heizer G, Llapur C, et al.
N Engl J Med
. 2022 May;
386(22):2084-2096.
PMID: 35507508
Background: Coronavirus-like particles (CoVLP) that are produced in plants and display the prefusion spike glycoprotein of the original strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are combined with...
7.
Pillet S, Arunachalam P, Andreani G, Golden N, Fontenot J, Aye P, et al.
Cell Mol Immunol
. 2022 Jan;
19(2):222-233.
PMID: 34983950
Although antivirals are important tools to control severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, effective vaccines are essential to control the current coronavirus disease 2019 (COVID-19) pandemic. Plant-derived virus-like...
8.
Ramjee L, Lemay W, Vurgun N, Charland N, Bauch C, Pullagura G, et al.
Hum Vaccin Immunother
. 2021 Jul;
17(10):3643-3651.
PMID: 34213404
Objective: The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada. Methods: Using Monte Carlo simulations, the...
9.
Makarkov A, Golizeh M, Ruiz-Lancheros E, Gopal A, Costas-Cancelas I, Chierzi S, et al.
NPJ Vaccines
. 2019 May;
4:17.
PMID: 31123605
A growing body of evidence supports the importance of T cell responses to protect against severe influenza, promote viral clearance, and ensure long-term immunity. Plant-derived virus-like particle (VLP) vaccines bearing...
10.
Won S, Hunt K, Guak H, Hasaj B, Charland N, Landry N, et al.
Vaccine
. 2018 Nov;
36(52):8028-8038.
PMID: 30448064
Cell-mediated immunity is an important component of immediate and long-term anti-viral protection. Dendritic cells (DCs) are essential for the induction of cell-mediated immunity by instructing the activation and differentiation of...