Nathalia Daflon-Yunes
Overview
Explore the profile of Nathalia Daflon-Yunes including associated specialties, affiliations and a list of published articles.
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7
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97
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Recent Articles
1.
Gozzi G, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Guragossian N, et al.
Drug Des Devel Ther
. 2015 Jul;
9:3481-95.
PMID: 26170632
Ketonic indeno[1,2-b]indole-9,10-dione derivatives, initially designed as human casein kinase II (CK2) inhibitors, were recently shown to be converted into efficient inhibitors of drug efflux by the breast cancer resistance protein...
2.
Gozzi G, Bouaziz Z, Winter E, Daflon-Yunes N, Aichele D, Nacereddine A, et al.
J Med Chem
. 2014 Oct;
58(1):265-77.
PMID: 25272055
A series of indeno[1,2-b]indole-9,10-dione derivatives were synthesized as human casein kinase II (CK2) inhibitors. The most potent inhibitors contained a N(5)-isopropyl substituent on the C-ring. The same series of compounds...
3.
Fonseca-de-Souza A, Freitas-Mesquita A, Vieira L, Majerowicz D, Daflon-Yunes N, Soares-de-Medeiros L, et al.
PLoS One
. 2014 Sep;
9(9):e106852.
PMID: 25203926
In this study, we performed the molecular and biochemical characterization of an ecto-enzyme present in Trypanosoma rangeli that is involved with the hydrolysis of extracellular inorganic pyrophosphate. PCR analysis identified...
4.
Moreira M, Bagni C, Pinho M, Mac-Cormick T, dos Santos Mota M, Pinto-Silva F, et al.
Leuk Res
. 2014 Jul;
38(8):983-7.
PMID: 24996974
Resistance to chemotherapy is one of the most relevant aspects of treatment failure in cancer. Cell lines are used as models to study resistance. We analyzed the transcriptional profile of...
5.
Winter E, Gozzi G, Domeneghini Chiaradia-Delatorre L, Daflon-Yunes N, Terreux R, Gauthier C, et al.
Drug Des Devel Ther
. 2014 Jun;
8:609-19.
PMID: 24920885
A series of chalcones substituted by a quinoxaline unit at the B-ring were synthesized and tested as inhibitors of breast cancer resistance protein-mediated mitoxantrone efflux. These compounds appeared more efficient...
6.
Daflon-Yunes N, Pinto-Silva F, Vidal R, Novis B, Berguetti T, Lopes R, et al.
Mol Cell Biochem
. 2013 Jul;
383(1-2):123-35.
PMID: 23877223
The multidrug-resistant (MDR) phenotype is multifactorial, and cell lines presenting multiple resistance mechanisms might be good models to understand the importance of the various pathways involved. The present work characterized...
7.
Russo-Abrahao T, Cosentino-Gomes D, Daflon-Yunes N, Meyer-Fernandes J
Exp Parasitol
. 2010 Jul;
127(1):66-71.
PMID: 20599434
In this work, we biochemically characterized the ecto-5'-nucleotidase activity present on the surface of the living trophozoites of Giardia duodenalis. Two sequences of the 5'-nucleotidase family protein were identified in...