Nataliya Petryk
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Explore the profile of Nataliya Petryk including associated specialties, affiliations and a list of published articles.
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14
Citations
700
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Recent Articles
1.
Fajri N, Petryk N
Commun Biol
. 2024 Jun;
7(1):729.
PMID: 38877080
Before each cell division, eukaryotic cells must replicate their chromosomes to ensure the accurate transmission of genetic information. Chromosome replication involves more than just DNA duplication; it also includes chromatin...
2.
Wu X, Liu Y, dAubenton-Carafa Y, Thermes C, Hyrien O, Chen C, et al.
Nat Protoc
. 2023 Jan;
18(4):1260-1295.
PMID: 36653528
Studying the dynamics of genome replication in mammalian cells has been historically challenging. To reveal the location of replication initiation and termination in the human genome, we developed Okazaki fragment...
3.
DeWeerd R, Nemeth E, Poti A, Petryk N, Chen C, Hyrien O, et al.
Cell Rep
. 2022 Mar;
38(12):110555.
PMID: 35320711
Mutational signatures defined by single base substitution (SBS) patterns in cancer have elucidated potential mutagenic processes that contribute to malignancy. Two prevalent mutational patterns in human cancers are attributed to...
4.
Petryk N, Reveron-Gomez N, Gonzalez-Aguilera C, Dalby M, Andersson R, Groth A
Nat Protoc
. 2021 Aug;
16(9):4446-4493.
PMID: 34363071
Elucidating the mechanisms underlying chromatin maintenance upon genome replication is critical for the understanding of how gene expression programs and cell identity are preserved across cell divisions. Here, we describe...
5.
Blin M, Lacroix L, Petryk N, Jaszczyszyn Y, Chen C, Hyrien O, et al.
Nucleic Acids Res
. 2021 Apr;
49(12):e69.
PMID: 33836085
The replication strategy of metazoan genomes is still unclear, mainly because definitive maps of replication origins are missing. High-throughput methods are based on population average and thus may exclusively identify...
6.
Petryk N, Bultmann S, Bartke T, Defossez P
Nucleic Acids Res
. 2020 Dec;
49(6):3020-3032.
PMID: 33300031
DNA methylation is essential to development and cellular physiology in mammals. Faulty DNA methylation is frequently observed in human diseases like cancer and neurological disorders. Molecularly, this epigenetic mark is...
7.
Stewart-Morgan K, Petryk N, Groth A
Nat Cell Biol
. 2020 Apr;
22(4):361-371.
PMID: 32231312
Propagation of the chromatin landscape across cell divisions is central to epigenetic cell memory. Mechanistic analysis of the interplay between DNA replication, the cell cycle, and the epigenome has provided...
8.
Wu X, Kabalane H, Kahli M, Petryk N, Laperrousaz B, Jaszczyszyn Y, et al.
Nucleic Acids Res
. 2018 Sep;
46(19):10532.
PMID: 30212853
No abstract available.
9.
Wu X, Kabalane H, Kahli M, Petryk N, Laperrousaz B, Jaszczyszyn Y, et al.
Nucleic Acids Res
. 2018 Sep;
46(19):10157-10172.
PMID: 30189101
The spatiotemporal program of metazoan DNA replication is regulated during development and altered in cancers. We have generated novel OK-seq, Repli-seq and RNA-seq data to compare the DNA replication and...
10.
Reveron-Gomez N, Gonzalez-Aguilera C, Stewart-Morgan K, Petryk N, Flury V, Graziano S, et al.
Mol Cell
. 2018 Aug;
72(2):239-249.e5.
PMID: 30146316
Chromatin organization is disrupted genome-wide during DNA replication. On newly synthesized DNA, nucleosomes are assembled from new naive histones and old modified histones. It remains unknown whether the landscape of...