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Nataliya Gorinski

Explore the profile of Nataliya Gorinski including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 724
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Recent Articles
1.
Stapel B, Xiao K, Gorinski N, Schmidt K, Pfanne A, Fiedler J, et al.
Front Psychiatry . 2022 Dec; 13:1020530. PMID: 36506422
Objective: Major depressive disorder (MDD) constitutes a main risk factor for suicide. Suicide risk in psychiatric patients is primarily determined by often unreliable, self-reported information. We assessed serum levels of...
2.
Wirth A, Labus J, Abdel Galil D, Schill Y, Schmidt S, Bunke T, et al.
J Biol Chem . 2022 May; 298(6):102048. PMID: 35597282
The small GTPase Cdc42 exists in the form of two alternatively spliced variants that are modified by hydrophobic chains: the ubiquitously expressed Cdc42-prenyl and a brain-specific isoform that can be...
3.
Bijata M, Baczynska E, Muller F, Bijata K, Masternak J, Krzystyniak A, et al.
Cell Rep . 2022 Mar; 38(11):110532. PMID: 35294881
Major depressive disorder is a complex disease resulting from aberrant synaptic plasticity that may be caused by abnormal serotonergic signaling. Using a combination of behavioral, biochemical, and imaging methods, we...
4.
Sonnenberg S, Rauer J, Gohr C, Gorinski N, Schade S, Abdel Galil D, et al.
J Cell Sci . 2021 Feb; 134(4). PMID: 33536244
Morphological remodeling of dendritic spines is critically involved in memory formation and depends on adhesion molecules. Serotonin receptors are also implicated in this remodeling, though the underlying mechanisms remain enigmatic....
5.
Gorinski N, Wojciechowski D, Guseva D, Abdel Galil D, Mueller F, Wirth A, et al.
J Biol Chem . 2020 Mar; 295(18):5970-5983. PMID: 32184353
Barttin is the accessory subunit of the human ClC-K chloride channels, which are expressed in both the kidney and inner ear. Barttin promotes trafficking of the complex it forms with...
6.
Stapel B, Gorinski N, Gmahl N, Rhein M, Preuss V, Hilfiker-Kleiner D, et al.
Expert Opin Ther Targets . 2019 Oct; 23(10):883-891. PMID: 31637934
In line with the monoamine hypothesis of major depressive disorder (MDD), the clinical efficacy of the selective serotonin reuptake inhibitor fluoxetine has classically been ascribed to central serotonin enhancing properties....
7.
Gorinski N, Bijata M, Prasad S, Wirth A, Abdel Galil D, Zeug A, et al.
Nat Commun . 2019 Sep; 10(1):3924. PMID: 31477731
The serotonergic system and in particular serotonin 1A receptor (5-HT1AR) are implicated in major depressive disorder (MDD). Here we demonstrated that 5-HT1AR is palmitoylated in human and rodent brains, and...
8.
Hohoff C, Zhang M, Ambree O, Kravchenko M, Buschert J, Kerkenberg N, et al.
Brain Struct Funct . 2019 Jun; 224(6):2213-2230. PMID: 31183559
The palmitoyl acyltransferase ZDHHC7 belongs to the DHHC family responsible for the covalent attachment of palmitic acid (palmitoylation) to target proteins. Among synaptic proteins, its main targets are sex steroid...
9.
Steinke K, Gorinski N, Wojciechowski D, Todorov V, Guseva D, Ponimaskin E, et al.
J Biol Chem . 2015 May; 290(28):17390-400. PMID: 26013830
CLC-K/barttin chloride channels are essential for NaCl re-absorption in Henle's loop and for potassium secretion by the stria vascularis in the inner ear. Here, we studied the posttranslational modification of...
10.
Berod L, Friedrich C, Nandan A, Freitag J, Hagemann S, Harmrolfs K, et al.
Nat Med . 2015 Apr; 21(4):414. PMID: 25849276
No abstract available.