Narendiran Rajasekaran
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Explore the profile of Narendiran Rajasekaran including associated specialties, affiliations and a list of published articles.
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Citations
272
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Recent Articles
11.
Zhao X, Chester C, Rajasekaran N, He Z, Kohrt H
Mol Cancer Ther
. 2016 May;
15(5):767-73.
PMID: 27197256
The dominant cancer treatment modalities such as chemotherapy, radiotherapy, and even targeted kinase inhibitors and mAbs are limited by low efficacy, toxicity, and treatment-resistant tumor subclones. Oncolytic viral therapy offers...
12.
Yonezawa A, Chester C, Rajasekaran N, Kohrt H
Chin Clin Oncol
. 2016 Mar;
5(1):5.
PMID: 26932429
No abstract available.
13.
Wang N, Rajasekaran N, Hou T, Macaubas C, Mellins E
PLoS One
. 2015 May;
10(5):e0128494.
PMID: 26020954
Type I diabetes (T1D), mediated by autoreactive T cell destruction of insulin-producing islet beta cells, has been treated with bone marrow-derived hematopoietic stem cell (BM-HSC) transplantation. Older non-obese diabetic (NOD)...
14.
Rajasekaran N, Tran R, Pascual C, Xie X, Mellins E
Open J Rheumatol Autoimmune Dis
. 2014 Dec;
4(1):62-68.
PMID: 25506517
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial hyperplasia and progressive cartilage and bone destruction that leads to a substantial loss of general functions and/or a...
15.
Macmillan H, Strohman M, Ayyangar S, Jiang W, Rajasekaran N, Spura A, et al.
J Immunol
. 2014 Aug;
193(6):2641-2650.
PMID: 25098292
B cells internalize extracellular Ag into endosomes using the Ig component of the BCR. In endosomes, Ag-derived peptides are loaded onto MHC class II proteins. How these pathways intersect remains...
16.
Singh A, Rajasekaran N, Hartenstein B, Szabowski S, Gajda M, Angel P, et al.
Arthritis Res Ther
. 2013 Dec;
15(6):R222.
PMID: 24369907
Introduction: Matrix metalloproteinases (MMPs) are important in tissue remodelling. Here we investigate the role of collagenase-3 (MMP-13) in antibody-induced arthritis. Methods: For this study we employed the K/BxN serum-induced arthritis...
17.
Wang N, Rajasekaran N, Hou T, Mellins E
Stem Cell Res
. 2013 Nov;
12(1):209-21.
PMID: 24270160
Gene therapy mediated by bone marrow-derived hematopoietic stem cells (BM-HSC) has been widely used in treating genetic deficiencies in both pre-clinical and clinical settings. Using mitotically inactive cell-targeting lentivirus with...
18.
Wang N, Rajasekaran N, Hou T, Lisowski L, Mellins E
Exp Hematol
. 2013 Aug;
41(11):934-43.
PMID: 23954710
HIV-derived lentiviral vectors have been used widely to transduce non-dividing cells, such as hematopoietic stem cells (HSCs), in the setting of gene therapy. In this study, we screened lentiviral vectors...
19.
Rajasekaran N, Wang N, Truong P, Rinderknecht C, Macaubas C, Beilhack G, et al.
Arthritis Rheum
. 2012 Dec;
65(3):681-92.
PMID: 23233229
Objective: In the K/BxN mouse model of inflammatory arthritis, T cells carrying a transgenic T cell receptor initiate disease by helping B cells to produce arthritogenic anti-glucose-6-phosphate isomerase (anti-GPI) autoantibodies....
20.
Rinderknecht C, Lu N, Crespo O, Truong P, Hou T, Wang N, et al.
Int Immunol
. 2010 Jun;
22(8):705-16.
PMID: 20547545
Several MHC class II alleles linked with autoimmune diseases form unusually low-stability complexes with class II-associated invariant chain peptides (CLIP), leading us to hypothesize that this is an important feature...