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Naomi Kashiwazaki

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Articles 74
Citations 508
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Recent Articles
1.
Kawata Y, Terakawa J, Takeshita A, Namiki T, Kageyama A, Noguchi M, et al.
PNAS Nexus . 2025 Feb; 4(2):pgaf047. PMID: 39967682
Zinc is a critical trace element that is important for various biological functions including male and female reproductive systems, but the molecular mechanisms that underlie fertility have been unclear. We...
2.
Kageyama A, Terakawa J, Takarabe S, Sugita H, Kawata Y, Ito J, et al.
J Reprod Dev . 2024 Jul; 70(5):338-342. PMID: 39048372
Zinc is an essential trace element for various physiological functions, including reproduction. The influx/efflux of zinc ions is regulated by zinc transporters (Zip1-14 and ZnT1-8, 10). However, the precise roles...
3.
Kamoshita M, Sugita H, Kageyama A, Kawata Y, Ito J, Kashiwazaki N
Anim Sci J . 2024 Feb; 95(1):e13931. PMID: 38400795
Vitrification is a valuable technology that enables semipermanent preservation and long-distance or international transportation of genetically modified and native animals. In laboratory mice, vitrification maintains and transports embryos, and many...
4.
Kageyama A, Tsuchiya M, Terakawa J, Ito J, Kashiwazaki N
J Reprod Dev . 2023 Jun; 69(4):223-226. PMID: 37331813
Superovulation procedures are routinely and widely used in mouse reproductive technology. Previous studies have shown that a large number of oocytes can be obtained from adult mice (> 10 weeks...
5.
Hirose N, Kikuchi Y, Kageyama A, Sugita H, Sakurai M, Kawata Y, et al.
Life (Basel) . 2023 Apr; 13(4). PMID: 37109509
During mammalian fertilization, repetitive rises of intracellular calcium called calcium oscillations are required for full activation of oocytes. Therefore, oocytes such as round spermatid injected or somatic cell nuclear transferred...
6.
Namiki T, Terakawa J, Karakama H, Noguchi M, Murakami H, Hasegawa Y, et al.
Sci Rep . 2023 Jan; 13(1):854. PMID: 36646738
Leukemia inhibitory factor (LIF) receptor, an interleukin 6 cytokine family signal transducer (Il6st, also known as Gp130) that is expressed in the uterine epithelium and stroma, has been recognized to...
7.
Ishii M, Kamoshita M, Kurihara Y, Matsumura K, Hyon S, Ito J, et al.
J Reprod Dev . 2022 Dec; 69(1):53-55. PMID: 36503905
The vitrification of zygotes is important for their use as donors for generating genome-edited mice. We previously reported the successful vitrification of mouse zygotes using carboxylated ε-poly-L-lysine (COOH-PLL). However, this...
8.
Kageyama A, Suyama A, Kinoshita R, Ito J, Kashiwazaki N
Anim Sci J . 2022 Jul; 93(1):e13759. PMID: 35880318
Although it is well known that calcium oscillations are required for fertilization in all mammalian species studied to date, recent studies also showed the ejection of zinc into the extracellular...
9.
Namiki T, Kamoshita M, Kageyama A, Terakawa J, Ito J, Kashiwazaki N
Anim Sci J . 2021 Aug; 92(1):e13615. PMID: 34402137
In mice, the conditional knockout strategy using the Cre-loxP system is useful for various types of research. The Cre mouse line with progesterone receptor promoter (Pgr ) has been widely...
10.
Kawano H, Yamashita N, Ito J, Kashiwazaki N
Reprod Med Biol . 2021 Jul; 20(3):260-266. PMID: 34262393
Purpose: Although giant oocytes (GOs) having about twice cytoplasmic volume compared with general oocytes in mammals including the human are rarely recovered, it is thought that GOs have potentially chromosomal...