Nao Iguchi
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Explore the profile of Nao Iguchi including associated specialties, affiliations and a list of published articles.
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13
Citations
63
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Recent Articles
1.
Iguchi N, Teimouri A, Wilcox D, Malykhina A, Cost N
Sci Rep
. 2025 Feb;
15(1):4530.
PMID: 39915615
No abstract available.
2.
Iguchi N, Teimouri A, Wilcox D, Malykhina A, Cost N
Sci Rep
. 2024 Jul;
14(1):15049.
PMID: 38951167
Vincristine (VCR) is one of the most widely used chemotherapy agents in treating pediatric cancer. Nonetheless, it is known to cause dose-dependent neurotoxicity which can impact virtually every organ system....
3.
Xie A, Iguchi N, Malykhina A
Am J Physiol Renal Physiol
. 2024 Apr;
326(6):F957-F970.
PMID: 38601986
Stretch-activated two-pore domain K (K) channels play important roles in many visceral organs, including the urinary bladder. The TWIK-related K channel TREK-1 is the predominantly expressed K channel in the...
4.
Iguchi N, Donmez M, Malykhina A, Wilcox D
Investig Clin Urol
. 2023 Mar;
64(2):189-196.
PMID: 36882179
Purpose: To investigate potential beneficial effects of tocotrienols which have been suggested to inhibit hypoxia-inducible factor (HIF) pathway, on partial bladder outlet obstruction (PBOO)-induced bladder pathology. Materials And Methods: PBOO...
5.
Clarkson T, Iguchi N, Xie A, Malykhina A
PLoS One
. 2022 Dec;
17(12):e0278918.
PMID: 36490282
Multiple sclerosis (MS) often leads to the development of neurogenic lower urinary tract symptoms (LUTS). We previously characterized neurogenic bladder dysfunction in a mouse model of MS induced by a...
6.
Iguchi N, Hecht S, Gao D, Wilcox D, Malykhina A, Cost N
Sci Rep
. 2022 Mar;
12(1):5113.
PMID: 35332157
Vincristine (VCR) is one of the most common chemotherapy agents used in pediatric oncology. Despite the well-known VCR-induced peripheral neuropathy, potential impacts of VCR on lower urinary tract (LUT) function...
7.
Xie A, Iguchi N, Clarkson T, Malykhina A
PLoS One
. 2022 Jan;
17(1):e0262769.
PMID: 35077502
The study investigated the cellular and molecular mechanisms in the peripheral nervous system (PNS) underlying the symptoms of urologic chronic pelvic pain syndrome (UCPPS) in mice. This work also aimed...
8.
Hecht S, Quach A, Gao D, Brazell A, Beltran G, Holbrook S, et al.
Pediatr Blood Cancer
. 2021 Jul;
68(10):e29226.
PMID: 34245214
Background: Two chemotherapeutic agents used widely in pediatric oncology are vincristine (VCR) and doxorubicin (DOX), which may cause neuropathy and myopathy, respectively. The study hypothesis is that neurotoxic effects of...
9.
Iguchi N, Carrasco Jr A, Xie A, Pineda R, Malykhina A, Wilcox D
Sci Rep
. 2021 Jan;
11(1):1149.
PMID: 33441874
Bladder and bowel dysfunction (BBD) is a common yet underdiagnosed paediatric entity that describes lower urinary tract symptoms (LUTS) accompanied by abnormal bowel patterns manifested as constipation and/or encopresis. LUTS...
10.
Pineda R, Hypolite J, Lee S, Carrasco Jr A, Iguchi N, Meacham R, et al.
BMC Urol
. 2019 May;
19(1):40.
PMID: 31113422
Background: Previously published results from our laboratory identified a mechano-gated two-pore domain potassium channel, TREK-1, as a main mechanosensor in the smooth muscle of the human urinary bladder. One of...