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Nannan Kong

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Citations 22
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Recent Articles
1.
Kong N, Chen K, Chanboonyasitt P, Jiang H, Wong K, Ma H, et al.
Nucleic Acids Res . 2024 Dec; 53(3). PMID: 39704103
Incomplete sister centromere decatenation results in centromeric ultrafine anaphase bridges (UFBs). PICH (PLK1-interacting checkpoint helicase), a DNA translocase, plays a crucial role in UFB resolution by recruiting UFB-binding proteins and...
2.
Liu S, Yao J, Lin L, Lan X, Wu L, He X, et al.
Cell Genom . 2024 Oct; 4(10):100657. PMID: 39389015
Metabolites are key indicators of health and therapeutic targets, but their genetic underpinnings during pregnancy-a critical period for human reproduction-are largely unexplored. Using genetic data from non-invasive prenatal testing, we...
3.
Liu Z, Jiang H, Lee S, Kong N, Chan Y
Cell Rep . 2024 Jul; 43(7):114464. PMID: 38985669
Poly(ADP-ribose) polymerase inhibitors (PARPis) exhibit remarkable anticancer activity in tumors with homologous recombination (HR) gene mutations. However, the role of other DNA repair proteins in PARPi-induced lethality remains elusive. Here,...
4.
Kong N, Chan Y
STAR Protoc . 2023 May; 4(2):102286. PMID: 37252842
We present here a protocol for biallelic tagging of an endogenous gene in human cells using CRISPR-Cas9 editing technology. Using RIF1 as an example, we describe tagging the gene with...
5.
Jiang H, Kong N, Liu Z, West S, Chan Y
Adv Sci (Weinh) . 2023 Feb; 10(12):e2204388. PMID: 36825683
Chromatin bridges connecting the two segregating daughter nuclei arise from chromosome fusion or unresolved interchromosomal linkage. Persistent chromatin bridges are trapped in the cleavage plane, triggering cytokinesis delay. The trapped...
6.
Ai H, Liu X, Hu Z, Cao Y, Kong N, Gao F, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768758
() encodes a protein localized to the endoplasmic reticulum (ER) and cell wall. This gene plays a key role in responding to phosphate (Pi) deprivation, especially in remodeling the root...
7.
Kong N, Liu Z, Chan Y
Cell Rep . 2023 Jan; 42(2):112032. PMID: 36719798
Resolution of ultrafine anaphase bridges (UFBs) must be completed before cytokinesis to ensure sister-chromatid disjunction. RIF1 is involved in UFB resolution by a mechanism that is not yet clear. Here,...
8.
Wang X, Wang Y, Zhao X, Chen B, Kong N, Shangguan L, et al.
Environ Sci Pollut Res Int . 2022 Apr; 29(41):62272-62280. PMID: 35397727
It has been well documented that polycyclic aromatic hydrocarbon (PAHs) can be taken up from the environment by the plants and translocated into the shoots. However, the mechanisms underlying this...
9.
Bao G, Kong N, Guo M, Su X, Kang H
Hua Xi Kou Qiang Yi Xue Za Zhi . 2015 Nov; 33(4):352-6. PMID: 26552235
Objective: This study is performed to investigate the cell topographies and biomechanical properties of two different types of temporomandibular joint (TMJ) discs from goats by using JPK Nano Wizard 3...
10.
Kong N, Zhou Y, Xu S, Deng Y, Fan Y, Zhang Y, et al.
J Proteome Res . 2015 Oct; 14(12):4967-75. PMID: 26456862
During an investigation of missing proteins with the RNA-seq data acquired from three liver cancer cell lines, the majority of the missing protein coding genes (MPGs) located at chromosome 11...