Nancy L Quinney
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Explore the profile of Nancy L Quinney including associated specialties, affiliations and a list of published articles.
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20
Citations
600
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Recent Articles
1.
Sun L, Walls S, Dang H, Quinney N, Sears P, Sadritabrizi T, et al.
bioRxiv
. 2024 Aug;
PMID: 39211176
Rationale: Hyper IgE syndrome (STAT3-HIES), also known as Job's syndrome, is a rare immunodeficiency disease typically caused by dominant-negative STAT3 mutations. STAT3-HIES syndrome is characterized by chronic pulmonary infection and...
2.
Gentzsch M, Baker B, Cholon D, Kam C, McKinzie C, Despotes K, et al.
ERJ Open Res
. 2024 Jan;
10(1).
PMID: 38226069
https://bit.ly/3tTcoJE.
3.
Cholon D, Greenwald M, Higgs M, Quinney N, Boyles S, Meinig S, et al.
Cells
. 2023 Nov;
12(22).
PMID: 37998353
People with cystic fibrosis (pwCF) suffer from chronic and recurring bacterial lung infections that begin very early in life and contribute to progressive lung failure. CF is caused by mutations...
4.
Ruan J, Liang D, Yan W, Zhong Y, Talley D, Rai G, et al.
Mol Biol Cell
. 2022 Sep;
33(13):ar120.
PMID: 36074076
RNF5 E3 ubiquitin ligase has multiple biological roles and has been linked to the development of severe diseases such as cystic fibrosis, acute myeloid leukemia, and certain viral infections, emphasizing...
5.
Ghigo A, Murabito A, Sala V, Pisano A, Bertolini S, Gianotti A, et al.
Sci Transl Med
. 2022 Mar;
14(638):eabl6328.
PMID: 35353541
Cyclic adenosine 3',5'-monophosphate (cAMP)-elevating agents, such as β-adrenergic receptor (β-AR) agonists and phosphodiesterase (PDE) inhibitors, remain a mainstay in the treatment of obstructive respiratory diseases, conditions characterized by airway constriction,...
6.
Morrison C, Shaffer K, Araba K, Markovetz M, Wykoff J, Quinney N, et al.
Eur Respir J
. 2021 Jun;
59(2).
PMID: 34172469
Question: Cystic fibrosis (CF) is characterised by the accumulation of viscous adherent mucus in the lungs. While several hypotheses invoke a direct relationship with cystic fibrosis transmembrane conductance regulator (CFTR)...
7.
Dang Y, van Heusden C, Nickerson V, Chung F, Wang Y, Quinney N, et al.
Nucleic Acids Res
. 2021 Jun;
49(11):6100-6113.
PMID: 34107015
Pulmonary diseases offer many targets for oligonucleotide therapeutics. However, effective delivery of oligonucleotides to the lung is challenging. For example, splicing mutations in the cystic fibrosis transmembrane conductance regulator (CFTR)...
8.
Gentzsch M, Cholon D, Quinney N, Martino M, Minges J, Boyles S, et al.
Front Pharmacol
. 2021 Apr;
12:628722.
PMID: 33859562
In cystic fibrosis (CF), defective biogenesis and activity of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to airway dehydration and impaired mucociliary clearance, resulting in chronic airway infection and...
9.
He L, Kennedy A, Houck S, Aleksandrov A, Quinney N, Cyr-Scully A, et al.
Mol Biol Cell
. 2021 Feb;
32(7):538-553.
PMID: 33534640
The transmembrane Hsp40 DNAJB12 and cytosolic Hsp70 cooperate on the endoplasmic reticulum's (ER) cytoplasmic face to facilitate the triage of nascent polytopic membrane proteins for folding versus degradation. N1303K is...
10.
Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, et al.
Am J Respir Crit Care Med
. 2020 Dec;
203(10):1275-1289.
PMID: 33321047
Identification of the specific cell types expressing CFTR (cystic fibrosis [CF] transmembrane conductance regulator) is required for precision medicine therapies for CF. However, a full characterization of CFTR expression in...