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Nancy Ernst

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Articles 10
Citations 236
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Recent Articles
1.
Egu D, Schmitt T, Ernst N, Ludwig R, Fuchs M, Hiermaier M, et al.
J Invest Dermatol . 2024 Apr; 144(11):2440-2452. PMID: 38642796
Pemphigus is a severe blistering disease caused by autoantibodies primarily against the desmosomal cadherins desmoglein (DSG)1 and DSG3, which impair desmosome integrity. Especially for the acute phase, additional treatment options...
2.
Limberg M, Weihrauch T, Gray N, Ernst N, Hartmann K, Raap U
Biomolecules . 2023 Jul; 13(7). PMID: 37509055
Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal...
3.
Zillikens H, Kasprick A, Osterloh C, Gross N, Radziewitz M, Hass C, et al.
Front Med (Lausanne) . 2021 Sep; 8:713312. PMID: 34557502
Class I phosphoinositide 3-kinases (PI3K) have been implemented in pathogenesis of experimental epidermolysis bullosa acquisita (EBA), an autoimmune skin disease caused by type VII collagen (COL7) autoantibodies. Mechanistically, inhibition of...
4.
Ohrvik H, Grujic M, Waern I, Gustafson A, Ernst N, Roers A, et al.
Oncotarget . 2016 Sep; 7(42):68990-69001. PMID: 27602499
Mast cells have been implicated in malignant processes, mainly through clinical correlative studies and by experiments performed using animals lacking mast cells due to defective c-kit signaling. However, mast cell-deficient...
5.
Kloepper J, Ernst N, Krieger K, Bodo E, Biro T, Haslam I, et al.
J Invest Dermatol . 2014 Feb; 134(7):2036-2038. PMID: 24518172
No abstract available.
6.
Ernst N, Yay A, Biro T, Tiede S, Humphries M, Paus R, et al.
PLoS One . 2014 Jan; 8(12):e84356. PMID: 24386370
β1 integrin regulates multiple epithelial cell functions by connecting cells with the extracellular matrix (ECM). While β1 integrin-mediated signaling in murine epithelial stem cells is well-studied, its role in human...
7.
Ernst N, Tiede S, Tronnier V, Kruse C, Zechel C, Paus R
Exp Dermatol . 2010 Jan; 19(6):549-55. PMID: 20100195
Human skin-derived Nestin+ cells serve as a convenient source for autologous, adult, pluripotent progenitor cells that offer new therapeutic possibilities in cell-based regenerative medicine. However, the isolation of human Nestin+...
8.
Tiede S, Kloepper J, Ernst N, Poeggeler B, Kruse C, Paus R
J Invest Dermatol . 2009 Jun; 129(11):2711-20. PMID: 19554024
Cutaneous nestin+ cells are of substantial interest in regenerative medicine. However, the location of nestin+ cells in situ remains controversial. We therefore sought to determine their location in female human...
9.
Tiede S, Ernst N, Bayat A, Paus R, Tronnier V, Zechel C
Ann Anat . 2008 Dec; 191(1):33-44. PMID: 19071002
Numerous tissue niches in the human body, such as skin, are now recognized to harbour adult stem cells. In this study, we analyze multipotent human dermis-derived progenitor cell populations, isolated...
10.
Kondgen S, Kuhl H, NGoran P, Walsh P, Schenk S, Ernst N, et al.
Curr Biol . 2008 Jan; 18(4):260-4. PMID: 18222690
Commercial hunting and habitat loss are major drivers of the rapid decline of great apes [1]. Ecotourism and research have been widely promoted as a means of providing alternative value...