Nancy E LePard
Overview
Explore the profile of Nancy E LePard including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
299
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0
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Recent Articles
1.
Bosiljcic M, Cederberg R, Hamilton M, LePard N, Harbourne B, Collier J, et al.
Breast Cancer Res
. 2019 Sep;
21(1):103.
PMID: 31488209
Background: Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine...
2.
Dickman C, Lawson J, Jabalee J, MacLellan S, LePard N, Bennewith K, et al.
Oncotarget
. 2017 Feb;
8(9):15252-15266.
PMID: 28146434
Packaging of small molecular factors, including miRNAs, into small extracellular vesicles (SEVs) may contribute to malignant phenotypes and facilitate communication between cancer cells and tumor stroma. The process by which...
3.
Hamilton M, Halvorsen E, LePard N, Bosiljcic M, Ho V, Lam V, et al.
Oncotarget
. 2015 Dec;
7(4):3677-91.
PMID: 26683227
SH2-containing-inositol-5'-phosphatase (SHIP) is a negative regulator of the phosphatidylinositol-3-kinase pathway in hematopoietic cells and limits the development of leukemias and lymphomas. The potential role of SHIP in solid tumor development...
4.
El-Naggar A, Veinotte C, Cheng H, Grunewald T, Negri G, Somasekharan S, et al.
Cancer Cell
. 2015 May;
27(5):682-97.
PMID: 25965573
Metastatic dissemination is the leading cause of death in cancer patients, which is particularly evident for high-risk sarcomas such as Ewing sarcoma, osteosarcoma, and rhabdomyosarcoma. Previous research identified a crucial...
5.
Hamilton M, Bosiljcic M, LePard N, Halvorsen E, Ho V, Banath J, et al.
J Immunol
. 2013 Nov;
192(1):512-22.
PMID: 24285836
Myeloid-derived suppressor cells (MDSCs) are emerging as potential promoters of metastatic tumor growth, and there is interest in targeting immature MDSCs by inducing their differentiation into more mature myeloid cells....
6.
Hamilton M, Banath J, Lam V, LePard N, Krystal G, Bennewith K
Cancer Immunol Immunother
. 2011 Oct;
61(5):643-54.
PMID: 22021068
As more groups investigate the role of myeloid-derived suppressor cells (MDSCs) in promoting the growth of primary tumors and distant tumor metastases, it is imperative to ensure the accurate detection...
7.
Bosiljcic M, Hamilton M, Banath J, LePard N, McDougal D, Jia J, et al.
Cancer Res
. 2011 Jul;
71(14):5050-1.
PMID: 21750177
4T1 murine mammary carcinoma cells implanted in syngeneic Balb/c mice are increasingly being used in metastasis research, with some groups using this model to study tumor-induced accumulation of bone marrow-derived...