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Namjong Choi

Explore the profile of Namjong Choi including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 444
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Recent Articles
1.
Hochman S, Madaline T, Wassmer S, Mbale E, Choi N, Seydel K, et al.
mBio . 2016 Feb; 7(1):e02068-15. PMID: 26838718
No abstract available.
2.
Hochman S, Madaline T, Wassmer S, Mbale E, Choi N, Seydel K, et al.
mBio . 2015 Sep; 6(5):e01390-15. PMID: 26396242
Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of...
3.
Suh H, Lo Y, Choi N, Letendre S, Lee S
J Neuroinflammation . 2015 Apr; 12:72. PMID: 25890304
Background: Clinically significant dysregulation of the insulin-like growth factor (IGF) family proteins occurs in HIV-infected individuals, but the details including whether the deficiencies in IGFs contribute to CNS dysfunction are...
4.
Suh H, Lo Y, Choi N, Letendre S, Lee S
PLoS One . 2014 Jun; 9(5):e98184. PMID: 24878635
Background: Compelling data exist that show that normal levels of progranulin (PGRN) are required for successful CNS aging. PGRN production is also modulated by inflammation and infection, but no data...
5.
Suh H, Zhao M, Derico L, Choi N, Lee S
J Neuroinflammation . 2013 Mar; 10:37. PMID: 23497056
Background: Recent studies in experimental animals show that insulin-like growth factor 1 (IGF1) plays a trophic role during development and tissue injury and that microglia are important sources of IGF1....
6.
Suh H, Choi N, Tarassishin L, Lee S
PLoS One . 2012 Apr; 7(4):e35115. PMID: 22509390
Background: The essential role of progranulin (PGRN) as a neurotrophic factor has been demonstrated by the discovery that haploinsufficiency due to GRN gene mutations causes frontotemporal lobar dementia. In addition...
7.
Krause D, Suh H, Tarassishin L, Cui Q, Durafourt B, Choi N, et al.
Am J Pathol . 2011 Aug; 179(3):1360-72. PMID: 21855684
Tryptophan metabolism by the kynurenine pathway (KP) is important to the pathogenesis of inflammatory, infectious, and degenerative diseases. The 3-hydroxykynurenine (3-HK) branch of the KP is activated in macrophages and...
8.
Suh H, Cosenza-Nashat M, Choi N, Zhao M, Li J, Pollard J, et al.
Am J Pathol . 2010 Oct; 177(5):2446-58. PMID: 20889566
Insulin-like growth factor 2 receptor (IGF2R), also known as cation-independent mannose 6-phosphate (M6P) receptor, is a transmembrane glycoprotein localized in the trans-Golgi region and is involved in targeting both M6P-bearing...
9.
Suh H, Choi S, Khattar P, Choi N, Lee S
J Neuroimmune Pharmacol . 2010 Feb; 5(4):521-32. PMID: 20157787
Histone deacetylase inhibitors (HDACi) have been proposed as therapies for certain cancers and as an anti-reservoir therapy for HIV+ individuals with highly active anti-retroviral therapy, yet their roles in glial...
10.
Suh H, Zhao M, Choi N, Belbin T, Brosnan C, Lee S
Virology . 2009 Aug; 392(2):246-59. PMID: 19646728
In the CNS, microglia are the primary targets of HIV infection. In this study, we investigated the effect of activation of the innate antiviral receptors TLR3 and TLR4 on HIV...