Naicheng Chen
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Explore the profile of Naicheng Chen including associated specialties, affiliations and a list of published articles.
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10
Citations
49
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Recent Articles
1.
Zeng H, Chen N, Chen F, Zhong X, Yang L, Lu Y, et al.
Cell Commun Signal
. 2024 Dec;
22(1):582.
PMID: 39627813
Ionizing radiation (IR) can cause severe dysfunction of hematopoietic stem cells (HSCs), leading to acute or prolonged myelosuppression. In recent years, physical exercise has been recognized as a healthy lifestyle...
2.
Chen F, Lu Y, Xu Y, Chen N, Yang L, Zhong X, et al.
Nat Commun
. 2024 Aug;
15(1):6787.
PMID: 39117713
The maintenance of hematopoietic stem cell (HSC) functional integrity is essential for effective hematopoietic regeneration when suffering from injuries. Studies have shown that the innate immune pathways play crucial roles...
3.
Hu M, Chen N, Chen M, Chen F, Lu Y, Xu Y, et al.
Leukemia
. 2023 Apr;
37(6):1361-1374.
PMID: 37095209
Hematopoietic stem cells (HSCs) reside at the top of the hematopoietic hierarchy, exhibiting a unique capacity to self-renew and differentiate into all blood cells throughout the lifetime. However, how to...
4.
Yang L, Lu Y, Zhang Z, Chen Y, Chen N, Chen F, et al.
Exp Cell Res
. 2023 Apr;
427(2):113603.
PMID: 37075826
Hematopoietic toxicity due to ionizing radiation (IR) is a leading cause of death in nuclear incidents, occupational hazards, and cancer therapy. Oxymatrine (OM), an extract originating from the root of...
5.
Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation
Lu Y, Yang L, Shen M, Zhang Z, Wang S, Chen F, et al.
Leukemia
. 2023 Mar;
37(5):1039-1047.
PMID: 36997676
Hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs) have robust self-renewal potential, which is responsible for sustaining normal and malignant hematopoiesis, respectively. Although considerable efforts have been made to...
6.
Chen N, Quan Y, Chen M, Lu Y, Yang L, Wang S, et al.
Blood Adv
. 2023 Mar;
7(13):3199-3212.
PMID: 36920787
Hematopoietic stem cells (HSCs) possess great self-renewal and multidirectional differentiation abilities, which contribute to the continuous generation of various blood cells. Although many intrinsic and extrinsic factors have been found...
7.
Lu Y, Zhang Z, Wang S, Qi Y, Chen F, Xu Y, et al.
Stem Cell Reports
. 2022 Feb;
17(3):599-615.
PMID: 35148846
Mitochondria are fundamental but complex determinants for hematopoietic stem cell (HSC) maintenance. However, the factors involved in the regulation of mitochondrial metabolism in HSCs and the underlying mechanisms have not...
8.
Zhang Z, Lu Y, Qi Y, Xu Y, Wang S, Chen F, et al.
Leukemia
. 2022 Feb;
36(4):956-969.
PMID: 35110726
The cell cycle progression of hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells is precisely controlled by multiple regulatory factors. However, the underlying mechanisms are not fully understood....
9.
Qi Y, Chen S, Lu Y, Zhang Z, Wang S, Chen N, et al.
Free Radic Biol Med
. 2021 Aug;
174:144-156.
PMID: 34389464
Ionizing radiation (IR)-induced excessive reactive oxygen species (ROS) is an important contributor of the injury of hematopoietic system. Grape seed proanthocyanidin extract (GSPE) is a new type of antioxidant, whereas...
10.
Hu M, Lu Y, Wang S, Zhang Z, Qi Y, Chen N, et al.
Cell Death Differ
. 2021 Aug;
29(1):178-191.
PMID: 34363017
Hematopoietic stem cell (HSC) fate is tightly controlled by various regulators, whereas the underlying mechanism has not been fully uncovered due to the high heterogeneity of these populations. In this...