Nai-Kui Liu
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Explore the profile of Nai-Kui Liu including associated specialties, affiliations and a list of published articles.
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37
Citations
1039
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Recent Articles
1.
Qu W, Wu X, Wu W, Wang Y, Sun Y, Deng L, et al.
Neural Regen Res
. 2024 Jul;
20(5):1467-1482.
PMID: 39075913
JOURNAL/nrgr/04.03/01300535-202505000-00029/figure1/v/2024-07-28T173839Z/r/image-tiff Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties. A the Food and...
2.
Lee D, Cao D, Moon Y, Chen C, Liu N, Xu X, et al.
Neural Regen Res
. 2024 Jun;
20(3):836-844.
PMID: 38886956
JOURNAL/nrgr/04.03/01300535-202503000-00028/figure1/v/2024-06-17T092413Z/r/image-tiff Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes...
3.
Liu N, Deng L, Wang M, Lu Q, Wang C, Wu X, et al.
Cell Death Dis
. 2022 Dec;
13(12):1058.
PMID: 36539405
Alterations in phospholipids have long been associated with spinal cord injury (SCI). However, their specific roles and signaling cascades in mediating cell death and tissue repair remain unclear. Here we...
4.
Wu W, Nguyen T, Ordaz J, Zhang Y, Liu N, Hu X, et al.
JCI Insight
. 2022 May;
7(12).
PMID: 35552276
Understanding the reorganization of neural circuits spared after spinal cord injury in the motor cortex and spinal cord would provide insights for developing therapeutics. Using optogenetic mapping, we demonstrated a...
5.
Deng L, Liu N, Wen R, Yang S, Wen X, Xu X
Neural Regen Res
. 2020 Aug;
16(1):186-191.
PMID: 32788475
Biomaterial bridging provides physical substrates to guide axonal growth across the lesion. To achieve efficient directional guidance, combinatory strategies using permissive matrix, cells and trophic factors are necessary. In the...
6.
Qu W, Liu N, Wu X, Wang Y, Xia Y, Sun Y, et al.
Cereb Cortex
. 2020 Jan;
30(7):3859-3871.
PMID: 31989159
Excessive activation of N-methyl-D-aspartate receptors (NMDARs) and the resulting neuronal nitric oxide synthase (nNOS) activation plays a crucial role in the pathogenesis of traumatic brain injury (TBI). However, directly inhibiting...
7.
Han Q, Ordaz J, Liu N, Richardson Z, Wu W, Xia Y, et al.
Nat Commun
. 2019 Dec;
10(1):5815.
PMID: 31862889
Locomotor function, mediated by lumbar neural circuitry, is modulated by descending spinal pathways. Spinal cord injury (SCI) interrupts descending projections and denervates lumbar motor neurons (MNs). We previously reported that...
8.
Walker C, Wu X, Liu N, Xu X
J Neurotrauma
. 2019 Jan;
36(18):2676-2687.
PMID: 30672370
Although mechanisms involved in progression of cell death in spinal cord injury (SCI) have been studied extensively, few are clear targets for translation to clinical application. One of the best-understood...
9.
Walker C, Fry C, Wang J, Du X, Zuzzio K, Liu N, et al.
J Neurotrauma
. 2018 Nov;
36(12):1974-1984.
PMID: 30489213
Spinal cord injury (SCI) afflicts hundreds of thousands of Americans, and most SCI (∼80%) occurs in males. In experimental animal models, however, many studies used females. Funding agencies like the...
10.
Wang Y, Wu W, Wu X, Sun Y, Zhang Y, Deng L, et al.
Elife
. 2018 Sep;
7.
PMID: 30207538
Retrogradely-transported neurotrophin signaling plays an important role in regulating neural circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to lumbar motoneurons (MNs) caudal to a thoracic (T10)...