Nadja Zeltner
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Explore the profile of Nadja Zeltner including associated specialties, affiliations and a list of published articles.
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33
Citations
738
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Recent Articles
11.
Wu H, Huang C, Art J, Liu H, Hart G, Zeltner N
Front Neurosci
. 2023 May;
17:1137847.
PMID: 37229433
O-GlcNAcylation is a post-translational modification (PTM) that regulates a wide range of cellular functions and has been associated with multiple metabolic diseases in various organs. The sympathetic nervous system (SNS)...
12.
Saito-Diaz K, James C, Patel A, Zeltner N
Front Cell Dev Biol
. 2023 May;
11:1101423.
PMID: 37206924
Sensory neurons (SNs) detect a wide range of information from the body and the environment that is critical for homeostasis. There are three main subtypes of SNs: nociceptors, mechanoreceptors, and...
13.
Huang C, Rust N, Wu H, Yin A, Zeltner N, Yin H, et al.
Alzheimers Dement
. 2023 Apr;
19(11):4872-4885.
PMID: 37037474
Introduction: Sporadic Alzheimer's disease (sAD) is the leading type of dementia. Brain glucose hypometabolism, along with decreased O-GlcNAcylation levels, occurs before the onset of symptoms and correlates with pathogenesis. Heretofore,...
14.
Saito-Diaz K, Dietrich P, Wu H, Sun X, Patel A, Wzientek C, et al.
bioRxiv
. 2023 Mar;
PMID: 36993570
The peripheral nervous system (PNS) is essential for proper body function. A high percentage of the population suffer nerve degeneration or peripheral damage. For example, over 40% of patients with...
15.
Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models
Wu H, Yu W, Saito-Diaz K, Huang C, Carey J, Lefcort F, et al.
Nat Commun
. 2022 Nov;
13(1):7032.
PMID: 36396637
Familial dysautonomia (FD), a rare neurodevelopmental and neurodegenerative disorder affects the sympathetic and sensory nervous system. Although almost all patients harbor a mutation in ELP1, it remains unresolved exactly how...
16.
Latchoumane C, Chopra P, Sun L, Ahmed A, Palmieri F, Wu H, et al.
ACS Appl Mater Interfaces
. 2022 Jun;
14(25):28476-28488.
PMID: 35708492
Three-dimensional (3D) synthetic heparan sulfate (HS) constructs possess promising attributes for neural tissue engineering applications. However, their sulfation-dependent ability to facilitate molecular recognition and cell signaling has not yet been...
17.
Saito-Diaz K, Zeltner N
STAR Protoc
. 2022 Mar;
3(2):101187.
PMID: 35330962
Human pluripotent stem cells (hPSCs) show promise for studying diseases affecting cell populations that are not easily available, including sensory neurons (SNs). Here, we present a differentiation protocol in chemically...
18.
Wu H, Huang C, Daga K, Marklein R, Ivanova N, Zeltner N
Clin Auton Res
. 2022 Jan;
32(1):59-63.
PMID: 35091835
No abstract available.
19.
Saito-Diaz K, Street J, Ulrichs H, Zeltner N
Stem Cell Reports
. 2021 Feb;
16(3):446-457.
PMID: 33545066
The three peripheral sensory neuron (SN) subtypes, nociceptors, mechanoreceptors, and proprioceptors, localize to dorsal root ganglia and convey sensations such as pain, temperature, pressure, and limb movement/position. Despite previous reports,...
20.
Mus L, Van Haver S, Popovic M, Trypsteen W, Lefever S, Zeltner N, et al.
Genes Chromosomes Cancer
. 2020 Dec;
60(4):272-281.
PMID: 33336840
Human embryonic stem cells (hESCs) and embryonal tumors share a number of common features, including a compromised G1/S checkpoint. Consequently, these rapidly dividing hESCs and cancer cells undergo elevated levels...