Nadine R Ottoson
Overview
Explore the profile of Nadine R Ottoson including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
30
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0
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Recent Articles
1.
Chan A, Kangas T, Qiu X, Uhlik M, Fulton R, Ottoson N, et al.
Front Oncol
. 2022 Jun;
12:869078.
PMID: 35692755
Imprime PGG (Imprime) is in late-stage clinical development as a combinatorial agent with several therapeutic modalities. Here we present pre-clinical mechanistic data supportive of Imprime, a soluble yeast β-1,3/1,6-glucan pathogen-associated...
2.
Bose N, Ottoson N, Qiu X, Harrison B, Lowe J, Uhlik M, et al.
J Immunol
. 2019 Apr;
202(10):2945-2956.
PMID: 30988115
Imprime PGG (Imprime) is an i.v. administered, yeast β-1,3/1,6 glucan in clinical development with checkpoint inhibitors. Imprime-mediated innate immune activation requires immune complex formation with naturally occurring IgG anti-β glucan...
3.
Chan A, Jonas A, Qiu X, Ottoson N, Walsh R, Gorden K, et al.
PLoS One
. 2016 Nov;
11(11):e0165909.
PMID: 27812183
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecular pattern...