Nadine M Melhem
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Explore the profile of Nadine M Melhem including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Tsui F, Ruiz V, Ryan N, Shi L, Melhem N, Young J, et al.
JAMA Netw Open
. 2024 Oct;
7(10):e2438144.
PMID: 39378032
Importance: Suicide is a leading cause of death in US youths. Objective: To assess whether screening with supplemental items 10 to 13 on the Patient Health Questionnaire-9 modified for teens...
2.
Davis M, Dysart G, Doupnik S, Hamm M, Schwartz K, George-Milford B, et al.
Acad Pediatr
. 2024 Jan;
24(4):645-653.
PMID: 38190885
Objective: To understand adolescent, parent, and provider perceptions of a machine learning algorithm for detecting adolescent suicide risk prior to its implementation primary care. Methods: We conducted semi-structured, qualitative interviews...
3.
Thoma B, Hone E, Roig A, Goodfriend E, Jardas E, Brummitt B, et al.
JAMA Netw Open
. 2023 Sep;
6(9):e2333060.
PMID: 37682570
Importance: The months following inpatient psychiatric hospitalization are a period of high risk for suicidal behavior. Sexual and gender minority (SGM) individuals have elevated risk for suicidal behavior, but no...
4.
Gibson B, Goodfriend E, Zhong Y, Melhem N
Transl Psychiatry
. 2023 Jun;
13(1):224.
PMID: 37355708
Inflammation contributes to numerous neuropsychiatric disorders, especially those that first appear in childhood. Maternal intrauterine environment, including the placenta, has a role in brain development and risk for neuropsychiatric disorders....
5.
Brent D, Melhem N
J Am Acad Child Adolesc Psychiatry
. 2023 Jun;
62(11):1191-1193.
PMID: 37328142
Prevention can be powerful. In the current issue of this Journal, Sandler et al. report on the long-term effects of the Family Bereavement Program (FBP), an intervention designed to promote...
6.
Pantazatos S, Ogden T, Melhem N, Brent D, Lesanpezeshki M, Burke A, et al.
J Psychiatr Res
. 2023 May;
163:262-269.
PMID: 37244064
Mood disorders and suicidal behavior have moderate heritability and familial transmission, and are associated with smaller hippocampal volumes. However, it is unclear whether hippocampal alterations reflect heritable risk or epigenetic...
7.
Pantazatos S, Melhem N, Brent D, Zanderigo F, Bartlett E, Lesanpezeshki M, et al.
Mol Psychiatry
. 2022 Jun;
27(10):4136-4143.
PMID: 35760877
Mood disorders and suicidal behavior have moderate heritability and are associated with altered corticolimbic serotonin 1A receptor (5-HT) brain binding. However, it is unclear whether this reflects genetic effects or...
8.
Marengo L, Douaihy A, Zhong Y, Krancevich K, Brummit B, Sakolsky D, et al.
Suicide Life Threat Behav
. 2021 Nov;
52(2):199-213.
PMID: 34767271
Introduction: There is a concomitant rise in suicide rates with the prevalence of opioids involved in overdose deaths, especially among adolescents and young adults. However, there are limited studies on...
9.
Melhem N, Zhong Y, Miller J, Zanderigo F, Ogden R, Sublette M, et al.
Int J Neuropsychopharmacol
. 2021 Sep;
25(1):36-45.
PMID: 34555145
Background: The serotonin 1A (5-HT1A) receptor has been implicated in depression and suicidal behavior. Lower resting cortisol levels are associated with higher 5-HT1A receptor binding, and both differentiate suicide attempters...
10.
Melhem N, Brent D
Child Adolesc Ment Health
. 2021 Jun;
26(3):274-275.
PMID: 34190403
The consequences of the COVID-19 pandemic on risk for suicidal thoughts and behaviors (STBs) in children are still not fully known. However, COVID-19 and the mitigation strategies to limit its...