Nadia Stefanova
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Explore the profile of Nadia Stefanova including associated specialties, affiliations and a list of published articles.
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108
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2905
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Recent Articles
1.
Heras-Garvin A, Fellner L, Granata R, Wenning G, Stefanova N
J Neural Transm (Vienna)
. 2025 Feb;
PMID: 39954078
Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by abnormal accumulation of α-synuclein, progressive neuronal loss, motor impairment and widespread pathological changes, which include significant involvement of the...
2.
Backman E, Gardberg M, Luntamo L, Peurla M, Vahlberg T, Borghammer P, et al.
Ann Neurol
. 2025 Feb;
PMID: 39918108
Objective: To investigate the role of neuroinflammation in the substantia nigra pars compacta (SNc) across different parkinsonian disorders-Parkinson's disease (PD), progressive supranuclear palsy (PSP), and multiple system atrophy (MSA)-by examining...
3.
Lam I, Ndayisaba A, Lewis A, Fu Y, Sagredo G, Kuzkina A, et al.
Neuron
. 2025 Feb;
113(4):637.
PMID: 39894019
No abstract available.
4.
Lam I, Ndayisaba A, Lewis A, Fu Y, Sagredo G, Kuzkina A, et al.
Neuron
. 2024 Jul;
112(17):2886-2909.e16.
PMID: 39079530
The heterogeneity of protein-rich inclusions and its significance in neurodegeneration is poorly understood. Standard patient-derived iPSC models develop inclusions neither reproducibly nor in a reasonable time frame. Here, we developed...
5.
Chia R, Ray A, Shah Z, Ding J, Ruffo P, Fujita M, et al.
Neuron
. 2024 May;
112(13):2142-2156.e5.
PMID: 38701790
Multiple system atrophy (MSA) is an adult-onset, sporadic synucleinopathy characterized by parkinsonism, cerebellar ataxia, and dysautonomia. The genetic architecture of MSA is poorly understood, and treatments are limited to supportive...
6.
Ortner N, Sah A, Paradiso E, Shin J, Stojanovic S, Hammer N, et al.
JCI Insight
. 2023 Sep;
8(20.
PMID: 37698939
Germline de novo missense variants of the CACNA1D gene, encoding the pore-forming α1 subunit of Cav1.3 L-type Ca2+ channels (LTCCs), have been found in patients with neurodevelopmental and endocrine dysfunction,...
7.
Cheng A, Jia W, Finkelstein D, Stefanova N, Wang H, Sasaki T, et al.
Acta Pharmacol Sin
. 2023 Aug;
45(1):66-75.
PMID: 37605049
Multiple system atrophy (MSA) is a rare, fatal neurodegenerative disease characterized by the accumulation of misfolded α-synuclein (αSyn) in glial cells, leading to the formation of glial cytoplasmic inclusions (GCI)....
8.
Stefanova N, Wenning G
Nat Rev Neurosci
. 2023 Apr;
24(6):334-346.
PMID: 37085728
Multiple system atrophy (MSA) is a rare oligodendroglial α-synucleinopathy characterized by neurodegeneration in striatonigral and olivopontocerebellar regions and autonomic brain centres. It causes complex cumulative motor and non-motor disability with...
9.
Cheng A, Kawahata I, Wang Y, Jia W, Wang H, Sekimori T, et al.
Brain
. 2023 Apr;
146(8):3172-3180.
PMID: 37082980
Multiple system atrophy (MSA) is a neurodegenerative disease characterized by the accumulation of misfolded α-synuclein (αSyn) and myelin disruption. However, the mechanism underlying αSyn accumulation in MSA brains remains unclear....
10.
Dutta S, Hornung S, Taha H, Biggs K, Siddique I, Chamoun L, et al.
ACS Chem Neurosci
. 2023 Mar;
14(7):1238-1248.
PMID: 36920792
Synucleinopathies are a group of neurodegenerative diseases including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). These diseases are characterized by the aggregation and deposition...