Nadege Goutagny
Overview
Explore the profile of Nadege Goutagny including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
2152
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0
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Recent Articles
1.
Bodnar-Wachtel M, Huber A, Gorry J, Hacot S, Burlet D, Gerossier L, et al.
Life Sci Alliance
. 2023 Feb;
6(4).
PMID: 36746533
NLRP3 is a pattern recognition receptor with a well-documented role in inducing inflammasome assembly in response to cellular stress. Deregulation of its activity leads to many inflammatory disorders including gouty...
2.
Guey B, Bodnar-Wachtel M, Drouillard A, Eberhardt A, Pratviel M, Goutagny N, et al.
Front Oncol
. 2020 Oct;
10:1683.
PMID: 33042810
Inflammasomes are molecular complexes that trigger an inflammatory response upon detection of pathogens or danger signals. Recent studies suggest that they are also involved in cancer progression. However, their roles...
3.
Shekarian T, Sivado E, Jallas A, Depil S, Kielbassa J, Janoueix-Lerosey I, et al.
Sci Transl Med
. 2019 Oct;
11(515).
PMID: 31645452
Although immune checkpoint-targeted therapies are currently revolutionizing cancer care, only a minority of patients develop durable objective responses to anti-PD-1, PD-L1, and CTLA-4 therapy. Therefore, new therapeutic interventions are needed...
4.
Abravanel F, Goutagny N, Joffray R, Eichenlaub E, Baron S, Aversenq A, et al.
J Clin Virol
. 2019 Jan;
112:10-14.
PMID: 30658273
Background: Several unautomated anti-HEV diagnostic tests are presently available. Objective: We have evaluated the performance of the new automated VIDAS® ANTI-HEV IgM and IgG assays. Study Design: We assessed the...
5.
Ainouze M, Rochefort P, Parroche P, Roblot G, Tout I, Briat F, et al.
PLoS Pathog
. 2018 Aug;
14(8):e1007158.
PMID: 30089163
Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to avoid viral persistence, the immune response...
6.
Abravanel F, Goutagny N, Perret C, Lhomme S, Vischi F, Aversenq A, et al.
J Clin Virol
. 2017 Mar;
89:46-50.
PMID: 28249234
Background: High performance anti-hepatitis E virus (HEV) IgG assays are crucial for epidemiology. Objective: To evaluate the performance of 2 prototypes developed for the VIDAS automatic system for detecting anti-HEV...
7.
Deauvieau F, Ollion V, Doffin A, Achard C, Fonteneau J, Verronese E, et al.
Int J Cancer
. 2014 Jul;
136(5):1085-94.
PMID: 25046660
Dendritic cells (DCs) cross-present antigen (Ag) to initiate T-cell immunity against most infections and tumors. Natural killer (NK) cells are innate cytolytic lymphocytes that have emerged as key modulators of...
8.
Hasan U, Zannetti C, Parroche P, Goutagny N, Malfroy M, Roblot G, et al.
J Exp Med
. 2013 Jun;
210(7):1369-87.
PMID: 23752229
Human papillomavirus type 16 (HPV16) and other oncogenic viruses have been reported to deregulate immunity by suppressing the function of the double-stranded DNA innate sensor TLR9. However, the mechanisms leading...
9.
Le Mercier I, Poujol D, Sanlaville A, Sisirak V, Gobert M, Durand I, et al.
Cancer Res
. 2013 Jun;
73(15):4629-40.
PMID: 23722543
Plasmacytoid dendritic cells (pDC) are key regulators of antiviral immunity. In previous studies, we reported that pDC-infiltrating human primary breast tumors represent an independent prognostic factor associated with poor outcome....
10.
Sisirak V, Vey N, Goutagny N, Renaudineau S, Malfroy M, Thys S, et al.
Int J Cancer
. 2013 Feb;
133(3):771-8.
PMID: 23389942
We previously reported that plasmacytoid dendritic cells (pDCs) infiltrating breast tumors are impaired for their interferon-α (IFN-α) production, resulting in local regulatory T cells amplification. We designed our study to...