Nacho Aguilo
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Explore the profile of Nacho Aguilo including associated specialties, affiliations and a list of published articles.
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52
Citations
1112
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Recent Articles
11.
Perez I, Campos-Pardos E, Diaz C, Uranga S, Sayes F, Vicente F, et al.
Mol Ther Nucleic Acids
. 2022 Mar;
27:1235-1248.
PMID: 35282413
Cyclic (di)nucleotides act as universal second messengers endogenously produced by several pathogens. Specifically, the roles of c-di-AMP in immunity and virulence have been largely explored, although its contribution to the...
12.
Mata E, Tarancon R, Guerrero C, Moreo E, Moreau F, Uranga S, et al.
Sci Immunol
. 2021 Sep;
6(63):eabc2934.
PMID: 34559551
Bacillus Calmette-Guerin (BCG) is an attenuated bacterial vaccine used to protect against () in regions where infections are highly prevalent. BCG is currently delivered by the intradermal route, but alternative...
13.
Martin C, Marinova D, Aguilo N, Gonzalo-Asensio J
Vaccine
. 2021 Jul;
39(50):7277-7285.
PMID: 34238608
At its 100th birthday of its first administration to a newborn, BCG has been (and continues being) an inspiration for the construction and development of hundreds of new TB vaccine...
14.
Santiago L, Uranga-Murillo I, Arias M, Gonzalez-Ramirez A, Macias-Leon J, Moreo E, et al.
Biology (Basel)
. 2021 Apr;
10(3).
PMID: 33801808
Several hundred millions of people have been diagnosed of coronavirus disease 2019 (COVID-19), causing millions of deaths and a high socioeconomic burden. SARS-CoV-2, the causative agent of COVID-19, induces both...
15.
Broset E, Pardo-Seco J, Kanno A, Aguilo N, Dacosta A, Rivero-Calle I, et al.
EBioMedicine
. 2021 Mar;
65:103254.
PMID: 33711798
Background: The Bacillus Calmette-Guérin (BCG), the only vaccine against tuberculosis (TB) currently in use, has shown beneficial effects against unrelated infections and to enhance immune responses to vaccines. However, there...
16.
Esteso G, Aguilo N, Julian E, Ashiru O, Ho M, Martin C, et al.
Front Immunol
. 2021 Mar;
12:622995.
PMID: 33708215
Natural Killer cell receptors allow this heterogeneous immune population to efficiently fight both tumors and infection, so their use as immunotherapy agents is an active field of research. Cytokine activation,...
17.
Dijkman K, Aguilo N, Boot C, Hofman S, Sombroek C, Vervenne R, et al.
Cell Rep Med
. 2021 Feb;
2(1):100187.
PMID: 33521701
To fight tuberculosis, better vaccination strategies are needed. Live attenuated -derived vaccine, MTBVAC, is a promising candidate in the pipeline, proven to be safe and immunogenic in humans so far....
18.
Vierboom M, Dijkman K, Sombroek C, Hofman S, Boot C, Vervenne R, et al.
Cell Rep Med
. 2021 Feb;
2(1):100185.
PMID: 33521699
BCG vaccination can strengthen protection against pathogens through the induction of epigenetic and metabolic reprogramming of innate immune cells, a process called trained immunity. We and others recently demonstrated that...
19.
Tarancon R, Mata E, Uranga S, Gomez A, Marinova D, Otal I, et al.
EBioMedicine
. 2021 Jan;
64:103186.
PMID: 33478923
Background: Substantial recent advances in the comprehension of the molecular and cellular mechanisms behind asthma have evidenced the importance of the lung immune environment for disease outcome, making modulation of...
20.
Mata E, Farrell D, Ma R, Uranga S, Gomez A, Monzon M, et al.
PLoS Pathog
. 2020 Dec;
16(12):e1009061.
PMID: 33347499
Species belonging to the Mycobacterium tuberculosis Complex (MTBC) show more than 99% genetic identity but exhibit distinct host preference and virulence. The molecular genetic changes that underly host specificity and...