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N Singewald

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Articles 73
Citations 1335
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Recent Articles
1.
Zwanzger P, Singewald N, Bandelow B
Nervenarzt . 2021 Jan; 92(5):433-440. PMID: 33502576
Besides cognitive behavioral therapy (CBT), psychopharmacotherapy belongs to the first-line treatment approaches for anxiety disorders according to all national and international guidelines. According to studies and meta-analyses, modern antidepressants in...
2.
Pierre A, Regin Y, Van Schuerbeek A, Fritz E, Muylle K, Beckers T, et al.
Psychoneuroendocrinology . 2019 Sep; 110:104430. PMID: 31542636
Background: Obesity is a risk factor for stress-related mental disorders such as post-traumatic stress disorder. The underlying mechanism through which obesity affects mental health remains poorly understood but dysregulation of...
3.
Murphy C, Singewald N
Genes Brain Behav . 2017 Oct; 17(3):e12427. PMID: 29028150
The current treatment of post-traumatic stress disorder (PTSD), phobias and other anxiety disorders, remains insufficient particularly in producing long-lasting full symptom control. Dysfunctional fear processing is common in these disorders,...
4.
Whittle N, Maurer V, Murphy C, Rainer J, Bindreither D, Hauschild M, et al.
Transl Psychiatry . 2016 Dec; 6(12):e974. PMID: 27922638
Extinction-based exposure therapy is used to treat anxiety- and trauma-related disorders; however, there is the need to improve its limited efficacy in individuals with impaired fear extinction learning and to...
5.
Sosulina L, Strippel C, Romo-Parra H, Walter A, Kanyshkova T, Sartori S, et al.
J Neurophysiol . 2015 Sep; 114(4):2500-8. PMID: 26334021
Substance P (SP) is implicated in stress regulation and affective and anxiety-related behavior. Particularly high expression has been found in the main output region of the amygdala complex, the central...
6.
Fitzgerald P, Pinard C, Camp M, Feyder M, Sah A, Bergstrom H, et al.
Mol Psychiatry . 2015 Apr; 20(7):913. PMID: 25824301
No abstract available.
7.
Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler K
Pharmacol Ther . 2015 Jan; 149:150-90. PMID: 25550231
Pathological fear and anxiety are highly debilitating and, despite considerable advances in psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with PTSD, phobias, panic and other anxiety disorders....
8.
Fitzgerald P, Pinard C, Camp M, Feyder M, Sah A, Bergstrom H, et al.
Mol Psychiatry . 2014 Dec; 20(7):901-12. PMID: 25510511
Traumatic fear memories are highly durable but also dynamic, undergoing repeated reactivation and rehearsal over time. Although overly persistent fear memories underlie anxiety disorders, such as posttraumatic stress disorder, the...
9.
Sotnikov S, Markt P, Malik V, Chekmareva N, Naik R, Sah A, et al.
Transl Psychiatry . 2014 Feb; 4:e359. PMID: 24518397
The continuum of physiological anxiety up to psychopathology is not merely dependent on genes, but is orchestrated by the interplay of genetic predisposition, gene x environment and epigenetic interactions. Accordingly,...
10.
Singewald N, Guo L, Philippu A
Amino Acids . 2013 Nov; 8(1):47-58. PMID: 24186215
The posterior hypothalamus of conscious, freely moving rats was superfused with artificial cerebrospinal fluid through a push-pull cannula and the release of amino acids was determined in the superfusate. Under...